7DXJ

Human 46QHuntingtin-HAP40 complex structure

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Huntingtin	polymer	3167	351191.3	1	UniProt (P42858) Pfam (PF20926) Pfam (PF20925) Pfam (PF20927)	Homo sapiens (Human)	Huntington disease protein,HD protein
2	B (B)	40-kDa huntingtin-associated protein	polymer	371	39141.9	1	UniProt (P23610)	Homo sapiens (Human)	HAP40,CpG island protein,Factor VIII intron 22 protein

Sequence modifications

A: -28 - 9 (UniProt: P42858)
A: 10 - 34 (PDB: 7DXJ)
A: 35 - 3138 (UniProt: P42858)

PDB	External Database	Details
Arg 1234	Lys 1238	conflict
Asn 1716	Thr 1720	variant
His 2305	Tyr 2309	variant

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	390333.2
All*	Total formula weight	390333.2

*Water molecules are not included.