7DVD

The crystal structure of p53 DNA binding domain and PUMA complex

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D	Cellular tumor antigen p53	polymer	205	23229.3	4	UniProt (P04637) Pfam (PF00870) In PDB	Homo sapiens (Human)	Antigen NY-CO-13,Phosphoprotein p53,Tumor suppressor p53
2	E	Bcl-2-binding component 3, isoforms 1/2	polymer	15	1674.9	1	UniProt (Q9BXH1) In PDB	Homo sapiens	JFY-1,p53 up-regulated modulator of apoptosis
3	A, B, C, D	ZINC ION	non-polymer		65.4	4	Chemie (ZN)
4		water	water		18.0	89	Chemie (HOH)

Sequence modifications

A, B, C, D: 92 - 290 (UniProt: P04637)

PDB	External Database	Details
His 291	-	expression tag
His 292	-	expression tag
His 293	-	expression tag
His 294	-	expression tag
His 295	-	expression tag
His 296	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	5
	Total formula weight	94592.2
Non-Polymers*	Number of molecules	4
	Total formula weight	261.6
All*	Total formula weight	94853.8

*Water molecules are not included.