7DVD
The crystal structure of p53 DNA binding domain and PUMA complex
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Cellular tumor antigen p53 | polymer | 205 | 23229.3 | 4 | UniProt (P04637) Pfam (PF00870) | Homo sapiens (Human) | Antigen NY-CO-13,Phosphoprotein p53,Tumor suppressor p53 |
| 2 | E (E) | Bcl-2-binding component 3, isoforms 1/2 | polymer | 15 | 1674.9 | 1 | UniProt (Q9BXH1) | Homo sapiens | JFY-1,p53 up-regulated modulator of apoptosis |
| 3 | F, G, H, I (A, B, C, D) | ZINC ION | non-polymer | 65.4 | 4 | Chemie (ZN) | |||
| 4 | J, K, L, M, N (A, B, C, D, E) | water | water | 18.0 | 89 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 92 - 290 (UniProt: P04637)
| PDB | External Database | Details |
|---|---|---|
| His 291 | - | expression tag |
| His 292 | - | expression tag |
| His 293 | - | expression tag |
| His 294 | - | expression tag |
| His 295 | - | expression tag |
| His 296 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 5 |
| Total formula weight | 94592.2 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 261.6 | |
| All* | Total formula weight | 94853.8 |
