7DRW
Bovine 20S immunoproteasome in complex with two human PA28alpha-beta activators
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, Z (A, f) | Proteasome subunit alpha type-6 | polymer | 246 | 27432.5 | 2 | UniProt (Q2YDE4) Pfam (PF10584) Pfam (PF00227) | Bos taurus (Bovine) | |
| 2 | AA, B (B, h) | Proteasome subunit alpha type-2 | polymer | 234 | 25927.5 | 2 | UniProt (Q3T0Y5) Pfam (PF10584) Pfam (PF00227) | Bos taurus (Bovine) | |
| 3 | BA, C (C, j) | Proteasome subunit alpha type-4 | polymer | 261 | 29525.8 | 2 | UniProt (Q3ZCK9) Pfam (PF10584) Pfam (PF00227) | Bos taurus (Bovine) | |
| 4 | D, V (D, P) | Proteasome subunit alpha type-7 | polymer | 248 | 27911.9 | 2 | UniProt (Q3ZBG0) Pfam (PF10584) Pfam (PF00227) | Bos taurus (Bovine) | |
| 5 | E, W (E, R) | Proteasome subunit alpha type-5 | polymer | 241 | 26436.0 | 2 | UniProt (Q5E987) Pfam (PF10584) Pfam (PF00227) | Bos taurus (Bovine) | |
| 6 | F, X (F, b) | Proteasome subunit alpha type-1 | polymer | 263 | 29625.7 | 2 | UniProt (Q3T0X5) Pfam (PF10584) Pfam (PF00227) | Bos taurus (Bovine) | |
| 7 | G, Y (G, d) | Proteasome subunit alpha type-3 | polymer | 255 | 28441.2 | 2 | UniProt (Q58DU5) Pfam (PF10584) Pfam (PF00227) | Bos taurus (Bovine) | |
| 8 | H, K, M, O, R... (H, K, M, O, c...) | Proteasome activator complex subunit 2 | polymer | 239 | 27398.6 | 6 | UniProt (Q9UL46) Pfam (PF02251) Pfam (PF02252) | Homo sapiens (Human) | 11S regulator complex subunit beta,REG-beta,Activator of multicatalytic protease subunit 2,Proteasome activator 28 subunit beta,PA28beta |
| 9 | I, J, L, N, P... (I, J, L, N, Q...) | Proteasome activator complex subunit 1 | polymer | 249 | 28768.1 | 8 | UniProt (Q06323) Pfam (PF02251) Pfam (PF02252) | Homo sapiens (Human) | 11S regulator complex subunit alpha,REG-alpha,Activator of multicatalytic protease subunit 1,Interferon gamma up-regulated I-5111 protein,IGUP I-5111,Proteasome activator 28 subunit alpha,PA28alpha |
| 10 | CA, GA (k, S) | Proteasome subunit beta type-3 | polymer | 205 | 23016.9 | 2 | UniProt (P33672) Pfam (PF00227) | Bos taurus (Bovine) | Proteasome chain 13,Proteasome component C10-II,Proteasome theta chain |
| 11 | DA, HA (l, T) | Proteasome subunit beta type-2 | polymer | 201 | 22924.3 | 2 | UniProt (Q5E9K0) Pfam (PF00227) | Bos taurus (Bovine) | |
| 12 | EA, IA (m, U) | Proteasome subunit beta type-1 | polymer | 241 | 26278.1 | 2 | UniProt (Q2TBX6) Pfam (PF00227) | Bos taurus (Bovine) | |
| 13 | FA, JA (n, V) | Proteasome subunit beta type-4 | polymer | 264 | 29057.0 | 2 | UniProt (Q3T108) Pfam (PF00227) | Bos taurus (Bovine) | |
| 14 | KA, NA (W, Z) | Proteasome subunit beta type-9 | polymer | 219 | 23427.4 | 2 | UniProt (Q3SZC2) Pfam (PF00227) | Bos taurus (Bovine) | Proteasome subunit beta-1i |
| 15 | LA, OA (X, 1) | Proteasome subunit beta type-10 | polymer | 273 | 29128.3 | 2 | UniProt (Q3T0T1) Pfam (PF00227) Pfam (PF12465) | Bos taurus (Bovine) | Proteasome subunit beta-2i |
| 16 | MA, PA (Y, 2) | Proteasome subunit beta type-8 | polymer | 276 | 30304.3 | 2 | UniProt (Q3T112) Pfam (PF00227) | Bos taurus (Bovine) | Proteasome subunit beta-5i |
Sequence modifications
H, K, M, O, c, g: 1 - 239 (UniProt: Q9UL46)
| PDB | External Database | Details |
|---|---|---|
| Pro 89 | His 89 | variant |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 42 |
| Total formula weight | 1153410.7 | |
| All* | Total formula weight | 1153410.7 |
