7DRW

Bovine 20S immunoproteasome in complex with two human PA28alpha-beta activators

Functional Information from GO Data

Chain	GOid	namespace	contents
1	0000502	cellular_component	proteasome complex
1	0004175	molecular_function	endopeptidase activity
1	0004298	molecular_function	threonine-type endopeptidase activity
1	0005634	cellular_component	nucleus
1	0005737	cellular_component	cytoplasm
1	0005829	cellular_component	cytosol
1	0005839	cellular_component	proteasome core complex
1	0006508	biological_process	proteolysis
1	0008233	molecular_function	peptidase activity
1	0016787	molecular_function	hydrolase activity
1	0019774	cellular_component	proteasome core complex, beta-subunit complex
1	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
1	0051603	biological_process	proteolysis involved in protein catabolic process
1	1990111	cellular_component	spermatoproteasome complex
2	0000502	cellular_component	proteasome complex
2	0002376	biological_process	immune system process
2	0004175	molecular_function	endopeptidase activity
2	0004298	molecular_function	threonine-type endopeptidase activity
2	0005634	cellular_component	nucleus
2	0005654	cellular_component	nucleoplasm
2	0005737	cellular_component	cytoplasm
2	0005829	cellular_component	cytosol
2	0005839	cellular_component	proteasome core complex
2	0006508	biological_process	proteolysis
2	0008233	molecular_function	peptidase activity
2	0016787	molecular_function	hydrolase activity
2	0019774	cellular_component	proteasome core complex, beta-subunit complex
2	0030154	biological_process	cell differentiation
2	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
2	0045444	biological_process	fat cell differentiation
2	0051603	biological_process	proteolysis involved in protein catabolic process
2	1990111	cellular_component	spermatoproteasome complex
a	0000502	cellular_component	proteasome complex
a	0005515	molecular_function	protein binding
a	0005654	cellular_component	nucleoplasm
a	0005737	cellular_component	cytoplasm
a	0005829	cellular_component	cytosol
a	0006979	biological_process	response to oxidative stress
a	0008537	cellular_component	proteasome activator complex
a	0034515	cellular_component	proteasome storage granule
a	0061133	molecular_function	endopeptidase activator activity
a	0061136	biological_process	regulation of proteasomal protein catabolic process
a	0070062	cellular_component	extracellular exosome
a	0071357	biological_process	cellular response to type I interferon
a	2000045	biological_process	regulation of G1/S transition of mitotic cell cycle
A	0000502	cellular_component	proteasome complex
A	0000932	cellular_component	P-body
A	0005634	cellular_component	nucleus
A	0005737	cellular_component	cytoplasm
A	0005829	cellular_component	cytosol
A	0005839	cellular_component	proteasome core complex
A	0006511	biological_process	ubiquitin-dependent protein catabolic process
A	0019773	cellular_component	proteasome core complex, alpha-subunit complex
A	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
A	0051603	biological_process	proteolysis involved in protein catabolic process
b	0000502	cellular_component	proteasome complex
b	0002376	biological_process	immune system process
b	0005634	cellular_component	nucleus
b	0005737	cellular_component	cytoplasm
b	0005829	cellular_component	cytosol
b	0005839	cellular_component	proteasome core complex
b	0006511	biological_process	ubiquitin-dependent protein catabolic process
b	0019773	cellular_component	proteasome core complex, alpha-subunit complex
b	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
b	0051603	biological_process	proteolysis involved in protein catabolic process
B	0000502	cellular_component	proteasome complex
B	0000932	cellular_component	P-body
B	0005634	cellular_component	nucleus
B	0005737	cellular_component	cytoplasm
B	0005829	cellular_component	cytosol
B	0005839	cellular_component	proteasome core complex
B	0006511	biological_process	ubiquitin-dependent protein catabolic process
B	0019773	cellular_component	proteasome core complex, alpha-subunit complex
B	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
B	0051603	biological_process	proteolysis involved in protein catabolic process
c	0000502	cellular_component	proteasome complex
c	0005515	molecular_function	protein binding
c	0005654	cellular_component	nucleoplasm
c	0005737	cellular_component	cytoplasm
c	0005829	cellular_component	cytosol
c	0006979	biological_process	response to oxidative stress
c	0008537	cellular_component	proteasome activator complex
c	0016020	cellular_component	membrane
c	0034515	cellular_component	proteasome storage granule
c	0042802	molecular_function	identical protein binding
c	0061133	molecular_function	endopeptidase activator activity
c	0061136	biological_process	regulation of proteasomal protein catabolic process
c	0070062	cellular_component	extracellular exosome
c	0071357	biological_process	cellular response to type I interferon
c	2000045	biological_process	regulation of G1/S transition of mitotic cell cycle
C	0000502	cellular_component	proteasome complex
C	0000932	cellular_component	P-body
C	0005634	cellular_component	nucleus
C	0005737	cellular_component	cytoplasm
C	0005829	cellular_component	cytosol
C	0005839	cellular_component	proteasome core complex
C	0006511	biological_process	ubiquitin-dependent protein catabolic process
C	0019773	cellular_component	proteasome core complex, alpha-subunit complex
C	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
C	0051603	biological_process	proteolysis involved in protein catabolic process
d	0000502	cellular_component	proteasome complex
d	0005634	cellular_component	nucleus
d	0005737	cellular_component	cytoplasm
d	0005829	cellular_component	cytosol
d	0005839	cellular_component	proteasome core complex
d	0006511	biological_process	ubiquitin-dependent protein catabolic process
d	0019773	cellular_component	proteasome core complex, alpha-subunit complex
d	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
d	0051603	biological_process	proteolysis involved in protein catabolic process
D	0000502	cellular_component	proteasome complex
D	0005634	cellular_component	nucleus
D	0005737	cellular_component	cytoplasm
D	0005829	cellular_component	cytosol
D	0005839	cellular_component	proteasome core complex
D	0006511	biological_process	ubiquitin-dependent protein catabolic process
D	0019773	cellular_component	proteasome core complex, alpha-subunit complex
D	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
D	0051603	biological_process	proteolysis involved in protein catabolic process
e	0000502	cellular_component	proteasome complex
e	0005515	molecular_function	protein binding
e	0005654	cellular_component	nucleoplasm
e	0005737	cellular_component	cytoplasm
e	0005829	cellular_component	cytosol
e	0006979	biological_process	response to oxidative stress
e	0008537	cellular_component	proteasome activator complex
e	0034515	cellular_component	proteasome storage granule
e	0061133	molecular_function	endopeptidase activator activity
e	0061136	biological_process	regulation of proteasomal protein catabolic process
e	0070062	cellular_component	extracellular exosome
e	0071357	biological_process	cellular response to type I interferon
e	2000045	biological_process	regulation of G1/S transition of mitotic cell cycle
E	0000502	cellular_component	proteasome complex
E	0005634	cellular_component	nucleus
E	0005737	cellular_component	cytoplasm
E	0005829	cellular_component	cytosol
E	0005839	cellular_component	proteasome core complex
E	0006511	biological_process	ubiquitin-dependent protein catabolic process
E	0019773	cellular_component	proteasome core complex, alpha-subunit complex
E	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
E	0051603	biological_process	proteolysis involved in protein catabolic process
f	0000502	cellular_component	proteasome complex
f	0000932	cellular_component	P-body
f	0005634	cellular_component	nucleus
f	0005737	cellular_component	cytoplasm
f	0005829	cellular_component	cytosol
f	0005839	cellular_component	proteasome core complex
f	0006511	biological_process	ubiquitin-dependent protein catabolic process
f	0019773	cellular_component	proteasome core complex, alpha-subunit complex
f	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
f	0051603	biological_process	proteolysis involved in protein catabolic process
F	0000502	cellular_component	proteasome complex
F	0002376	biological_process	immune system process
F	0005634	cellular_component	nucleus
F	0005737	cellular_component	cytoplasm
F	0005829	cellular_component	cytosol
F	0005839	cellular_component	proteasome core complex
F	0006511	biological_process	ubiquitin-dependent protein catabolic process
F	0019773	cellular_component	proteasome core complex, alpha-subunit complex
F	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
F	0051603	biological_process	proteolysis involved in protein catabolic process
g	0000502	cellular_component	proteasome complex
g	0005515	molecular_function	protein binding
g	0005654	cellular_component	nucleoplasm
g	0005737	cellular_component	cytoplasm
g	0005829	cellular_component	cytosol
g	0006979	biological_process	response to oxidative stress
g	0008537	cellular_component	proteasome activator complex
g	0016020	cellular_component	membrane
g	0034515	cellular_component	proteasome storage granule
g	0042802	molecular_function	identical protein binding
g	0061133	molecular_function	endopeptidase activator activity
g	0061136	biological_process	regulation of proteasomal protein catabolic process
g	0070062	cellular_component	extracellular exosome
g	0071357	biological_process	cellular response to type I interferon
g	2000045	biological_process	regulation of G1/S transition of mitotic cell cycle
G	0000502	cellular_component	proteasome complex
G	0005634	cellular_component	nucleus
G	0005737	cellular_component	cytoplasm
G	0005829	cellular_component	cytosol
G	0005839	cellular_component	proteasome core complex
G	0006511	biological_process	ubiquitin-dependent protein catabolic process
G	0019773	cellular_component	proteasome core complex, alpha-subunit complex
G	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
G	0051603	biological_process	proteolysis involved in protein catabolic process
h	0000502	cellular_component	proteasome complex
h	0000932	cellular_component	P-body
h	0005634	cellular_component	nucleus
h	0005737	cellular_component	cytoplasm
h	0005829	cellular_component	cytosol
h	0005839	cellular_component	proteasome core complex
h	0006511	biological_process	ubiquitin-dependent protein catabolic process
h	0019773	cellular_component	proteasome core complex, alpha-subunit complex
h	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
h	0051603	biological_process	proteolysis involved in protein catabolic process
H	0000502	cellular_component	proteasome complex
H	0005515	molecular_function	protein binding
H	0005654	cellular_component	nucleoplasm
H	0005737	cellular_component	cytoplasm
H	0005829	cellular_component	cytosol
H	0006979	biological_process	response to oxidative stress
H	0008537	cellular_component	proteasome activator complex
H	0016020	cellular_component	membrane
H	0034515	cellular_component	proteasome storage granule
H	0042802	molecular_function	identical protein binding
H	0061133	molecular_function	endopeptidase activator activity
H	0061136	biological_process	regulation of proteasomal protein catabolic process
H	0070062	cellular_component	extracellular exosome
H	0071357	biological_process	cellular response to type I interferon
H	2000045	biological_process	regulation of G1/S transition of mitotic cell cycle
i	0000502	cellular_component	proteasome complex
i	0005515	molecular_function	protein binding
i	0005654	cellular_component	nucleoplasm
i	0005737	cellular_component	cytoplasm
i	0005829	cellular_component	cytosol
i	0006979	biological_process	response to oxidative stress
i	0008537	cellular_component	proteasome activator complex
i	0034515	cellular_component	proteasome storage granule
i	0061133	molecular_function	endopeptidase activator activity
i	0061136	biological_process	regulation of proteasomal protein catabolic process
i	0070062	cellular_component	extracellular exosome
i	0071357	biological_process	cellular response to type I interferon
i	2000045	biological_process	regulation of G1/S transition of mitotic cell cycle
I	0000502	cellular_component	proteasome complex
I	0005515	molecular_function	protein binding
I	0005654	cellular_component	nucleoplasm
I	0005737	cellular_component	cytoplasm
I	0005829	cellular_component	cytosol
I	0006979	biological_process	response to oxidative stress
I	0008537	cellular_component	proteasome activator complex
I	0034515	cellular_component	proteasome storage granule
I	0061133	molecular_function	endopeptidase activator activity
I	0061136	biological_process	regulation of proteasomal protein catabolic process
I	0070062	cellular_component	extracellular exosome
I	0071357	biological_process	cellular response to type I interferon
I	2000045	biological_process	regulation of G1/S transition of mitotic cell cycle
j	0000502	cellular_component	proteasome complex
j	0000932	cellular_component	P-body
j	0005634	cellular_component	nucleus
j	0005737	cellular_component	cytoplasm
j	0005829	cellular_component	cytosol
j	0005839	cellular_component	proteasome core complex
j	0006511	biological_process	ubiquitin-dependent protein catabolic process
j	0019773	cellular_component	proteasome core complex, alpha-subunit complex
j	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
j	0051603	biological_process	proteolysis involved in protein catabolic process
J	0000502	cellular_component	proteasome complex
J	0005515	molecular_function	protein binding
J	0005654	cellular_component	nucleoplasm
J	0005737	cellular_component	cytoplasm
J	0005829	cellular_component	cytosol
J	0006979	biological_process	response to oxidative stress
J	0008537	cellular_component	proteasome activator complex
J	0034515	cellular_component	proteasome storage granule
J	0061133	molecular_function	endopeptidase activator activity
J	0061136	biological_process	regulation of proteasomal protein catabolic process
J	0070062	cellular_component	extracellular exosome
J	0071357	biological_process	cellular response to type I interferon
J	2000045	biological_process	regulation of G1/S transition of mitotic cell cycle
k	0000502	cellular_component	proteasome complex
k	0005634	cellular_component	nucleus
k	0005737	cellular_component	cytoplasm
k	0005829	cellular_component	cytosol
k	0005839	cellular_component	proteasome core complex
k	0019774	cellular_component	proteasome core complex, beta-subunit complex
k	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
k	0051603	biological_process	proteolysis involved in protein catabolic process
K	0000502	cellular_component	proteasome complex
K	0005515	molecular_function	protein binding
K	0005654	cellular_component	nucleoplasm
K	0005737	cellular_component	cytoplasm
K	0005829	cellular_component	cytosol
K	0006979	biological_process	response to oxidative stress
K	0008537	cellular_component	proteasome activator complex
K	0016020	cellular_component	membrane
K	0034515	cellular_component	proteasome storage granule
K	0042802	molecular_function	identical protein binding
K	0061133	molecular_function	endopeptidase activator activity
K	0061136	biological_process	regulation of proteasomal protein catabolic process
K	0070062	cellular_component	extracellular exosome
K	0071357	biological_process	cellular response to type I interferon
K	2000045	biological_process	regulation of G1/S transition of mitotic cell cycle
l	0000502	cellular_component	proteasome complex
l	0005634	cellular_component	nucleus
l	0005654	cellular_component	nucleoplasm
l	0005737	cellular_component	cytoplasm
l	0005829	cellular_component	cytosol
l	0005839	cellular_component	proteasome core complex
l	0006979	biological_process	response to oxidative stress
l	0010498	biological_process	proteasomal protein catabolic process
l	0019774	cellular_component	proteasome core complex, beta-subunit complex
l	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
l	0051603	biological_process	proteolysis involved in protein catabolic process
l	0061136	biological_process	regulation of proteasomal protein catabolic process
L	0000502	cellular_component	proteasome complex
L	0005515	molecular_function	protein binding
L	0005654	cellular_component	nucleoplasm
L	0005737	cellular_component	cytoplasm
L	0005829	cellular_component	cytosol
L	0006979	biological_process	response to oxidative stress
L	0008537	cellular_component	proteasome activator complex
L	0034515	cellular_component	proteasome storage granule
L	0061133	molecular_function	endopeptidase activator activity
L	0061136	biological_process	regulation of proteasomal protein catabolic process
L	0070062	cellular_component	extracellular exosome
L	0071357	biological_process	cellular response to type I interferon
L	2000045	biological_process	regulation of G1/S transition of mitotic cell cycle
m	0000502	cellular_component	proteasome complex
m	0005634	cellular_component	nucleus
m	0005737	cellular_component	cytoplasm
m	0005829	cellular_component	cytosol
m	0005839	cellular_component	proteasome core complex
m	0019774	cellular_component	proteasome core complex, beta-subunit complex
m	0051603	biological_process	proteolysis involved in protein catabolic process
M	0000502	cellular_component	proteasome complex
M	0005515	molecular_function	protein binding
M	0005654	cellular_component	nucleoplasm
M	0005737	cellular_component	cytoplasm
M	0005829	cellular_component	cytosol
M	0006979	biological_process	response to oxidative stress
M	0008537	cellular_component	proteasome activator complex
M	0016020	cellular_component	membrane
M	0034515	cellular_component	proteasome storage granule
M	0042802	molecular_function	identical protein binding
M	0061133	molecular_function	endopeptidase activator activity
M	0061136	biological_process	regulation of proteasomal protein catabolic process
M	0070062	cellular_component	extracellular exosome
M	0071357	biological_process	cellular response to type I interferon
M	2000045	biological_process	regulation of G1/S transition of mitotic cell cycle
n	0000502	cellular_component	proteasome complex
n	0005634	cellular_component	nucleus
n	0005654	cellular_component	nucleoplasm
n	0005737	cellular_component	cytoplasm
n	0005829	cellular_component	cytosol
n	0005839	cellular_component	proteasome core complex
n	0006979	biological_process	response to oxidative stress
n	0010498	biological_process	proteasomal protein catabolic process
n	0019774	cellular_component	proteasome core complex, beta-subunit complex
n	0036064	cellular_component	ciliary basal body
n	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
n	0051603	biological_process	proteolysis involved in protein catabolic process
n	0061136	biological_process	regulation of proteasomal protein catabolic process
N	0000502	cellular_component	proteasome complex
N	0005515	molecular_function	protein binding
N	0005654	cellular_component	nucleoplasm
N	0005737	cellular_component	cytoplasm
N	0005829	cellular_component	cytosol
N	0006979	biological_process	response to oxidative stress
N	0008537	cellular_component	proteasome activator complex
N	0034515	cellular_component	proteasome storage granule
N	0061133	molecular_function	endopeptidase activator activity
N	0061136	biological_process	regulation of proteasomal protein catabolic process
N	0070062	cellular_component	extracellular exosome
N	0071357	biological_process	cellular response to type I interferon
N	2000045	biological_process	regulation of G1/S transition of mitotic cell cycle
O	0000502	cellular_component	proteasome complex
O	0005515	molecular_function	protein binding
O	0005654	cellular_component	nucleoplasm
O	0005737	cellular_component	cytoplasm
O	0005829	cellular_component	cytosol
O	0006979	biological_process	response to oxidative stress
O	0008537	cellular_component	proteasome activator complex
O	0016020	cellular_component	membrane
O	0034515	cellular_component	proteasome storage granule
O	0042802	molecular_function	identical protein binding
O	0061133	molecular_function	endopeptidase activator activity
O	0061136	biological_process	regulation of proteasomal protein catabolic process
O	0070062	cellular_component	extracellular exosome
O	0071357	biological_process	cellular response to type I interferon
O	2000045	biological_process	regulation of G1/S transition of mitotic cell cycle
P	0000502	cellular_component	proteasome complex
P	0005634	cellular_component	nucleus
P	0005737	cellular_component	cytoplasm
P	0005829	cellular_component	cytosol
P	0005839	cellular_component	proteasome core complex
P	0006511	biological_process	ubiquitin-dependent protein catabolic process
P	0019773	cellular_component	proteasome core complex, alpha-subunit complex
P	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
P	0051603	biological_process	proteolysis involved in protein catabolic process
Q	0000502	cellular_component	proteasome complex
Q	0005515	molecular_function	protein binding
Q	0005654	cellular_component	nucleoplasm
Q	0005737	cellular_component	cytoplasm
Q	0005829	cellular_component	cytosol
Q	0006979	biological_process	response to oxidative stress
Q	0008537	cellular_component	proteasome activator complex
Q	0034515	cellular_component	proteasome storage granule
Q	0061133	molecular_function	endopeptidase activator activity
Q	0061136	biological_process	regulation of proteasomal protein catabolic process
Q	0070062	cellular_component	extracellular exosome
Q	0071357	biological_process	cellular response to type I interferon
Q	2000045	biological_process	regulation of G1/S transition of mitotic cell cycle
R	0000502	cellular_component	proteasome complex
R	0005634	cellular_component	nucleus
R	0005737	cellular_component	cytoplasm
R	0005829	cellular_component	cytosol
R	0005839	cellular_component	proteasome core complex
R	0006511	biological_process	ubiquitin-dependent protein catabolic process
R	0019773	cellular_component	proteasome core complex, alpha-subunit complex
R	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
R	0051603	biological_process	proteolysis involved in protein catabolic process
S	0000502	cellular_component	proteasome complex
S	0005634	cellular_component	nucleus
S	0005737	cellular_component	cytoplasm
S	0005829	cellular_component	cytosol
S	0005839	cellular_component	proteasome core complex
S	0019774	cellular_component	proteasome core complex, beta-subunit complex
S	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
S	0051603	biological_process	proteolysis involved in protein catabolic process
T	0000502	cellular_component	proteasome complex
T	0005634	cellular_component	nucleus
T	0005654	cellular_component	nucleoplasm
T	0005737	cellular_component	cytoplasm
T	0005829	cellular_component	cytosol
T	0005839	cellular_component	proteasome core complex
T	0006979	biological_process	response to oxidative stress
T	0010498	biological_process	proteasomal protein catabolic process
T	0019774	cellular_component	proteasome core complex, beta-subunit complex
T	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
T	0051603	biological_process	proteolysis involved in protein catabolic process
T	0061136	biological_process	regulation of proteasomal protein catabolic process
U	0000502	cellular_component	proteasome complex
U	0005634	cellular_component	nucleus
U	0005737	cellular_component	cytoplasm
U	0005829	cellular_component	cytosol
U	0005839	cellular_component	proteasome core complex
U	0019774	cellular_component	proteasome core complex, beta-subunit complex
U	0051603	biological_process	proteolysis involved in protein catabolic process
V	0000502	cellular_component	proteasome complex
V	0005634	cellular_component	nucleus
V	0005654	cellular_component	nucleoplasm
V	0005737	cellular_component	cytoplasm
V	0005829	cellular_component	cytosol
V	0005839	cellular_component	proteasome core complex
V	0006979	biological_process	response to oxidative stress
V	0010498	biological_process	proteasomal protein catabolic process
V	0019774	cellular_component	proteasome core complex, beta-subunit complex
V	0036064	cellular_component	ciliary basal body
V	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
V	0051603	biological_process	proteolysis involved in protein catabolic process
V	0061136	biological_process	regulation of proteasomal protein catabolic process
W	0000502	cellular_component	proteasome complex
W	0002376	biological_process	immune system process
W	0004175	molecular_function	endopeptidase activity
W	0004298	molecular_function	threonine-type endopeptidase activity
W	0005634	cellular_component	nucleus
W	0005737	cellular_component	cytoplasm
W	0005829	cellular_component	cytosol
W	0005839	cellular_component	proteasome core complex
W	0006508	biological_process	proteolysis
W	0008233	molecular_function	peptidase activity
W	0016787	molecular_function	hydrolase activity
W	0019774	cellular_component	proteasome core complex, beta-subunit complex
W	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
W	0051603	biological_process	proteolysis involved in protein catabolic process
W	1990111	cellular_component	spermatoproteasome complex
X	0000502	cellular_component	proteasome complex
X	0004175	molecular_function	endopeptidase activity
X	0004298	molecular_function	threonine-type endopeptidase activity
X	0005634	cellular_component	nucleus
X	0005737	cellular_component	cytoplasm
X	0005829	cellular_component	cytosol
X	0005839	cellular_component	proteasome core complex
X	0006508	biological_process	proteolysis
X	0008233	molecular_function	peptidase activity
X	0016787	molecular_function	hydrolase activity
X	0019774	cellular_component	proteasome core complex, beta-subunit complex
X	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
X	0051603	biological_process	proteolysis involved in protein catabolic process
X	1990111	cellular_component	spermatoproteasome complex
Y	0000502	cellular_component	proteasome complex
Y	0002376	biological_process	immune system process
Y	0004175	molecular_function	endopeptidase activity
Y	0004298	molecular_function	threonine-type endopeptidase activity
Y	0005634	cellular_component	nucleus
Y	0005654	cellular_component	nucleoplasm
Y	0005737	cellular_component	cytoplasm
Y	0005829	cellular_component	cytosol
Y	0005839	cellular_component	proteasome core complex
Y	0006508	biological_process	proteolysis
Y	0008233	molecular_function	peptidase activity
Y	0016787	molecular_function	hydrolase activity
Y	0019774	cellular_component	proteasome core complex, beta-subunit complex
Y	0030154	biological_process	cell differentiation
Y	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
Y	0045444	biological_process	fat cell differentiation
Y	0051603	biological_process	proteolysis involved in protein catabolic process
Y	1990111	cellular_component	spermatoproteasome complex
Z	0000502	cellular_component	proteasome complex
Z	0002376	biological_process	immune system process
Z	0004175	molecular_function	endopeptidase activity
Z	0004298	molecular_function	threonine-type endopeptidase activity
Z	0005634	cellular_component	nucleus
Z	0005737	cellular_component	cytoplasm
Z	0005829	cellular_component	cytosol
Z	0005839	cellular_component	proteasome core complex
Z	0006508	biological_process	proteolysis
Z	0008233	molecular_function	peptidase activity
Z	0016787	molecular_function	hydrolase activity
Z	0019774	cellular_component	proteasome core complex, beta-subunit complex
Z	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
Z	0051603	biological_process	proteolysis involved in protein catabolic process
Z	1990111	cellular_component	spermatoproteasome complex

Functional Information from PROSITE/UniProt

site_id	PS00388
Number of Residues	23
Details	PROTEASOME_ALPHA_1 Proteasome alpha-type subunits signature. YdlsaStFSPdGRvfQVEYAmkA

Chain	Residue	Details
G	TYR8-ALA30
E	TYR8-ALA30
F	TYR6-ALA28
A	PHE9-ALA31
h	TYR6-ALA28
D	TYR3-ALA25
j	TYR5-ALA27

---

site_id	PS00854
Number of Residues	48
Details	PROTEASOME_BETA_1 Proteasome beta-type subunits signature. MAMkGknCVAIAADrrfgiqaqmvttdfq.KifpmgdrlyiglaGlaTD

Chain	Residue	Details
k	MET12-ASP59
l	ILE5-ASP52
X	ALA43-ASP90
Y	LEU76-ASP123
m	LEU41-ASP88
n	LEU57-ASP104
W	MET24-ASP71
j	LEU35-ASP82

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	6
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"UniProtKB","id":"P60900","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	4
Details	Modified residue: {"description":"N6-acetyllysine","evidences":[{"source":"UniProtKB","id":"P60900","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	2
Details	Modified residue: {"description":"Phosphotyrosine","evidences":[{"source":"UniProtKB","id":"Q9QUM9","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	6
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"UniProtKB","id":"P25787","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	4
Details	Modified residue: {"description":"Phosphotyrosine","evidences":[{"source":"UniProtKB","id":"P25787","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI6
Number of Residues	4
Details	Modified residue: {"description":"N6-acetyllysine","evidences":[{"source":"UniProtKB","id":"P25787","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI7
Number of Residues	2
Details	Modified residue: {"description":"Phosphotyrosine","evidences":[{"source":"UniProtKB","id":"P17220","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI8
Number of Residues	6
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"UniProtKB","id":"P25789","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI9
Number of Residues	4
Details	Modified residue: {"description":"N6-acetyllysine","evidences":[{"source":"UniProtKB","id":"P25789","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI10
Number of Residues	2
Details	Modified residue: {"description":"Phosphotyrosine","evidences":[{"source":"UniProtKB","id":"O14818","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI11
Number of Residues	2
Details	Modified residue: {"description":"N6-acetyllysine","evidences":[{"source":"UniProtKB","id":"O14818","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI12
Number of Residues	8
Details	Glycosylation: {"description":"O-linked (GlcNAc) serine","evidences":[{"evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI13
Number of Residues	6
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"UniProtKB","id":"P28066","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI14
Number of Residues	2
Details	Modified residue: {"description":"Phosphothreonine","evidences":[{"source":"UniProtKB","id":"P28066","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI15
Number of Residues	2
Details	Modified residue: {"description":"Phosphoserine; alternate","evidences":[{"source":"UniProtKB","id":"P25786","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI16
Number of Residues	2
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"UniProtKB","id":"P25786","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI17
Number of Residues	2
Details	Glycosylation: {"description":"O-linked (GlcNAc) serine; alternate","evidences":[{"evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI18
Number of Residues	6
Details	Cross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin)","evidences":[{"source":"UniProtKB","id":"P25786","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI19
Number of Residues	6
Details	Modified residue: {"description":"N6-acetyllysine","evidences":[{"source":"UniProtKB","id":"P25788","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI20
Number of Residues	2
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"UniProtKB","id":"P25788","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI21
Number of Residues	6
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"20068231","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI22
Number of Residues	2
Details	Modified residue: {"description":"N-acetylserine","evidences":[{"source":"UniProtKB","id":"P49720","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI23
Number of Residues	2
Details	Modified residue: {"description":"N6-acetyllysine","evidences":[{"source":"UniProtKB","id":"P49720","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI24
Number of Residues	2
Details	Modified residue: {"description":"N-acetylmethionine","evidences":[{"source":"UniProtKB","id":"P49721","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI25
Number of Residues	6
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"UniProtKB","id":"P20618","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI26
Number of Residues	2
Details	Modified residue: {"description":"Phosphotyrosine","evidences":[{"source":"UniProtKB","id":"O09061","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI27
Number of Residues	2
Details	Modified residue: {"description":"N6-acetyllysine","evidences":[{"source":"UniProtKB","id":"P20618","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI28
Number of Residues	2
Details	Modified residue: {"description":"Phosphotyrosine","evidences":[{"source":"UniProtKB","id":"P28070","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI29
Number of Residues	6
Details	Active site: {"description":"Nucleophile","evidences":[{"evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI30
Number of Residues	4
Details	Modified residue: {"description":"N6-acetyllysine","evidences":[{"source":"UniProtKB","id":"P28065","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI31
Number of Residues	2
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"UniProtKB","id":"P40306","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---