7DMY
The crystal structure of Cpd7 in complex with BPTF bromodomain
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Nucleosome-remodeling factor subunit BPTF | polymer | 144 | 16927.1 | 1 | UniProt (Q12830) Pfam (PF00439) In PDB | Homo sapiens (Human) | Bromodomain and PHD finger-containing transcription factor,Fetal Alz-50 clone 1 protein,Fetal Alzheimer antigen |
2 | A | tert-butyl 3-methyl-2-[[(3R,5R)-1-methyl-5-phenyl-piperidin-3-yl]amino]-4-oxidanylidene-5,7-dihydropyrrolo[3,4-d]pyrimidine-6-carboxylate | non-polymer | 439.6 | 1 | Chemie (HAF) | |||
3 | water | water | 18.0 | 15 | Chemie (HOH) |
Sequence modifications
A: 2791 - 2911 (UniProt: Q12830)
PDB | External Database | Details |
---|---|---|
Met 2768 | - | initiating methionine |
His 2769 | - | expression tag |
His 2770 | - | expression tag |
His 2771 | - | expression tag |
His 2772 | - | expression tag |
His 2773 | - | expression tag |
His 2774 | - | expression tag |
Ser 2775 | - | expression tag |
Ser 2776 | - | expression tag |
Gly 2777 | - | expression tag |
Val 2778 | - | expression tag |
Asp 2779 | - | expression tag |
Leu 2780 | - | expression tag |
Gly 2781 | - | expression tag |
Thr 2782 | - | expression tag |
Glu 2783 | - | expression tag |
Asn 2784 | - | expression tag |
Leu 2785 | - | expression tag |
Tyr 2786 | - | expression tag |
Phe 2787 | - | expression tag |
Gln 2788 | - | expression tag |
Ser 2789 | - | expression tag |
Met 2790 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 16927.1 | |
Non-Polymers* | Number of molecules | 1 |
Total formula weight | 439.6 | |
All* | Total formula weight | 17366.6 |