7DHZ
Arsenic-bound p53 DNA-binding domain mutant R249S
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Cellular tumor antigen p53 | polymer | 200 | 22435.5 | 2 | UniProt (P04637) Pfam (PF00870) | Homo sapiens (Human) | Antigen NY-CO-13,Phosphoprotein p53,Tumor suppressor p53 |
| 2 | C, F, G (A, B) | GLYCEROL | non-polymer | 92.1 | 3 | Chemie (GOL) | |||
| 3 | D, H (A, B) | ARSENIC | non-polymer | 74.9 | 2 | Chemie (ARS) | |||
| 4 | E, I (A, B) | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
| 5 | J, K (A, B) | water | water | 18.0 | 462 | Chemie (HOH) |
Sequence modifications
A, B: 94 - 293 (UniProt: P04637)
| PDB | External Database | Details |
|---|---|---|
| Ser 249 | Arg 249 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 44870.9 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 556.9 | |
| All* | Total formula weight | 45427.9 |
