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7DHY

Arsenic-bound p53 DNA-binding domain mutant G245S

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C, D
(A, B, C, D)
Cellular tumor antigen p53polymer20022535.64UniProt (P04637)
Pfam (PF00870)
Homo sapiens (Human)Antigen NY-CO-13,Phosphoprotein p53,Tumor suppressor p53
2E, G, L, O
(A, B, C, D)
ARSENICnon-polymer74.94Chemie (ARS)
3F, H, M, P
(A, B, C, D)
ZINC IONnon-polymer65.44Chemie (ZN)
4I, J, K, N, R...
(B, C, D)
GLYCEROLnon-polymer92.17Chemie (GOL)
5Q
(D)
SULFATE IONnon-polymer96.11Chemie (SO4)
6U, V, W, X
(A, B, C, D)
waterwater18.0517Chemie (HOH)
Sequence modifications
A, B, C, D: 94 - 293 (UniProt: P04637)
PDBExternal DatabaseDetails
Ser 245Gly 245engineered mutation
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight90142.4
Non-Polymers*Number of molecules16
Total formula weight1302.0
All*Total formula weight91444.5
*Water molecules are not included.

247536

PDB entries from 2026-01-14

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