7DEI
Structure of human ORP3 ORD domain in complex with PI(4)P
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Oxysterol-binding protein-related protein 3 | polymer | 388 | 44940.5 | 2 | UniProt (Q9H4L5) Pfam (PF01237) | Homo sapiens (Human) | OSBP-related protein 3 |
| 2 | C, D (A, B) | (2R)-3-{[(S)-hydroxy{[(1R,2R,3R,4R,5S,6R)-2,3,5,6-tetrahydroxy-4-(phosphonooxy)cyclohexyl]oxy}phosphoryl]oxy}propane-1,2-diyl dioctanoate | non-polymer | 666.6 | 2 | Chemie (PIF) | |||
| 3 | E, F (A, B) | water | water | 18.0 | 51 | Chemie (HOH) |
Sequence modifications
A, B: 504 - 887 (UniProt: Q9H4L5)
| PDB | External Database | Details |
|---|---|---|
| Gly 499 | - | expression tag |
| Ser 500 | - | expression tag |
| Pro 501 | - | expression tag |
| Glu 502 | - | expression tag |
| Phe 503 | - | expression tag |
| Ser 515 | Cys 515 | engineered mutation |
| Ser 520 | Cys 520 | engineered mutation |
| - | Asp 859 | deletion |
| Gly 860 | Asp 861 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 89881.1 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 1333.2 | |
| All* | Total formula weight | 91214.2 |
