7DEG
Cryo-EM structure of a heme-copper terminal oxidase dimer provides insights into its catalytic mechanism
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, D (A, D) | Cytochrome c oxidase subunit I | polymer | 587 | 65861.6 | 2 | UniProt (O67937) Pfam (PF00115) | Aquifex aeolicus (strain VF5) | |
| 2 | B, E (C, F) | Cytochrome oxidase subunit IIa | polymer | 32 | 3944.8 | 2 | UniProt (by SIFTS) (G0LWX8) | Aquifex aeolicus | |
| 3 | C, F (B, E) | Cytochrome oxidase subunit II | polymer | 147 | 16479.4 | 2 | UniProt (G5DGC8) Pfam (PF00116) | Aquifex aeolicus | |
| 4 | G, Q (A, D) | HEME-AS | non-polymer | 921.0 | 2 | Chemie (HAS) | |||
| 5 | H, R (A, D) | PROTOPORPHYRIN IX CONTAINING FE | non-polymer | 616.5 | 2 | Chemie (HEM) | |||
| 6 | I, S (A, D) | COPPER (II) ION | non-polymer | 63.5 | 2 | Chemie (CU) | |||
| 7 | J, T (A, D) | 2-[(2~{E},6~{E},10~{Z},14~{Z},18~{Z},23~{R})-3,7,11,15,19,23,27-heptamethyloctacosa-2,6,10,14,18-pentaenyl]naphthalene-1,4-dione | non-polymer | 639.0 | 2 | Chemie (DLX) | |||
| 8 | K, M, N, P, U... (A, C, D, F) | (1R)-2-{[{[(2S)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL (11E)-OCTADEC-11-ENOATE | non-polymer | 749.0 | 6 | Chemie (PGV) | |||
| 9 | L, V (A, D) | 1,2-Distearoyl-sn-glycerophosphoethanolamine | non-polymer | 748.1 | 2 | Chemie (3PE) | |||
| 10 | O, X (B, E) | DINUCLEAR COPPER ION | non-polymer | 127.1 | 2 | Chemie (CUA) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 172571.5 | |
| Non-Polymers* | Number of molecules | 18 |
| Total formula weight | 10724.3 | |
| All* | Total formula weight | 183295.8 |
