7DDX
Crystal structure of KANK1 S1179F mutant in complex wtih eIF4A1
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | KN motif and ankyrin repeat domains 1 | polymer | 257 | 27765.6 | 1 | UniProt (E9Q238) Pfam (PF12796) In PDB | Mus musculus (Mouse) | |
2 | B | Eukaryotic initiation factor 4A-I | polymer | 242 | 26809.8 | 1 | UniProt (P60843) Pfam (PF00270) In PDB | Mus musculus (Mouse) | eIF4A-I,ATP-dependent RNA helicase eIF4A-1 |
3 | A, B | SULFATE ION | non-polymer | 96.1 | 5 | Chemie (SO4) | |||
4 | A | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
5 | water | water | 18.0 | 13 | Chemie (HOH) |
Sequence modifications
A: 1088 - 1338 (UniProt: E9Q238)
B: 1 - 238 (UniProt: P60843)
PDB | External Database | Details |
---|---|---|
Gly 1082 | - | expression tag |
Pro 1083 | - | expression tag |
Gly 1084 | - | expression tag |
Ser 1085 | - | expression tag |
Glu 1086 | - | expression tag |
Phe 1087 | - | expression tag |
Phe 1179 | Ser 1179 | engineered mutation |
PDB | External Database | Details |
---|---|---|
Gly -3 | - | expression tag |
Pro -2 | - | expression tag |
Gly -1 | - | expression tag |
Ser 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 54575.4 | |
Non-Polymers* | Number of molecules | 6 |
Total formula weight | 572.4 | |
All* | Total formula weight | 55147.9 |