7DDX
Crystal structure of KANK1 S1179F mutant in complex wtih eIF4A1
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | KN motif and ankyrin repeat domains 1 | polymer | 257 | 27765.6 | 1 | UniProt (E9Q238) Pfam (PF12796) | Mus musculus (Mouse) | |
| 2 | B (B) | Eukaryotic initiation factor 4A-I | polymer | 242 | 26809.8 | 1 | UniProt (P60843) Pfam (PF00270) | Mus musculus (Mouse) | eIF4A-I,ATP-dependent RNA helicase eIF4A-1 |
| 3 | C, D, F, G, H (A, B) | SULFATE ION | non-polymer | 96.1 | 5 | Chemie (SO4) | |||
| 4 | E (A) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) PubChem (753) | |||
| 5 | I, J (A, B) | water | water | 18.0 | 13 | Chemie (HOH) |
Sequence modifications
A: 1088 - 1338 (UniProt: E9Q238)
B: 1 - 238 (UniProt: P60843)
| PDB | External Database | Details |
|---|---|---|
| Gly 1082 | - | expression tag |
| Pro 1083 | - | expression tag |
| Gly 1084 | - | expression tag |
| Ser 1085 | - | expression tag |
| Glu 1086 | - | expression tag |
| Phe 1087 | - | expression tag |
| Phe 1179 | Ser 1179 | engineered mutation |
| PDB | External Database | Details |
|---|---|---|
| Gly -3 | - | expression tag |
| Pro -2 | - | expression tag |
| Gly -1 | - | expression tag |
| Ser 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 54575.4 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 572.4 | |
| All* | Total formula weight | 55147.9 |
