7DDK

Crystal structures of Na+,K+-ATPase in complex with rostafuroxin

Replaces:  6KQ0

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, D (A, C)	Sodium/potassium-transporting ATPase subunit alpha-1	polymer	1016	112403.9	2	UniProt (P05024) Pfam (PF00690) Pfam (PF00122) Pfam (PF13246) Pfam (PF00702) Pfam (PF00689)	Sus scrofa (Pig)	Na(+)/K(+) ATPase alpha-1 subunit,Sodium pump subunit alpha-1
2	B, E (B, D)	Sodium/potassium-transporting ATPase subunit beta-1	polymer	303	35204.4	2	UniProt (P05027) Pfam (PF00287)	Sus scrofa (Pig)	Sodium/potassium-dependent ATPase subunit beta-1
3	C, F (G, E)	FXYD domain-containing ion transport regulator	polymer	65	7094.1	2	UniProt (Q58K79) Pfam (PF02038)	Sus scrofa (Pig)	Na+/K+ ATPase gamma subunit transcript variant a
4	G, H, I, J (F, H, I, J)	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		424.4	4	In PDB GlyTouCan (G42666HT)
5	AA, K, M, Y (C, A)	MAGNESIUM ION	non-polymer		24.3	4	Chemie (MG)
6	L, Z (A, C)	SODIUM ION	non-polymer		23.0	2	Chemie (NA)
7	CA, DA, EA, FA, GA... (C, A)	1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE	non-polymer		787.1	13	Chemie (PCW)
8	JA, T (C, A)	(3S,5R,8R,9S,10S,13S,14S,17S)-17-(furan-3-yl)-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,15,16-dodecahydro-1H-cyclopenta[a]phenanthrene-3,14,17-triol	non-polymer		374.5	2	Chemie (E4R)
9	BA, LA, MA, U, W... (C, D, E, A, B...)	CHOLESTEROL	non-polymer		386.7	6	Chemie (CLR)
10	KA, V (D, B)	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	2	Chemie (NAG)
11	NA, OA (A, C)	water	water		18.0	10	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	309404.9
Branched	Number of molecules	4
	Total formula weight	1697.6
Non-Polymers*	Number of molecules	29
	Total formula weight	13887.1
All*	Total formula weight	324989.7

*Water molecules are not included.