7DCU

Crystal structure of HSF2 DNA-binding domain in complex with 3-site HSE DNA (21 bp)

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C (A, B, C)	Heat shock factor protein 2	polymer	113	13462.2	3	UniProt (Q03933) Pfam (PF00447)	Homo sapiens (Human)	HSF 2,Heat shock transcription factor 2,HSTF 2
2	D (D)	DNA (5'-D(*TP*GP*CP*GP*TP*TP*CP*TP*AP*GP*AP*AP*TP*AP*TP*TP*CP*GP*CP*GP*G)-3')	polymer	21	6469.2	1		Homo sapiens
3	E (E)	DNA (5'-D(*AP*CP*CP*GP*CP*GP*AP*AP*TP*AP*TP*TP*CP*TP*AP*GP*AP*AP*CP*GP*C)-3')	polymer	21	6416.2	1		Homo sapiens
4	F, G, H (A, B, C)	SODIUM ION	non-polymer		23.0	3	Chemie (NA)
5	I, J, K, L, M (A, B, C, D, E)	water	water		18.0	438	Chemie (HOH)

Sequence modifications

A, B, C: 7 - 112 (UniProt: Q03933)

PDB	External Database	Details
Gly 0	-	expression tag
His 1	-	expression tag
His 2	-	expression tag
His 3	-	expression tag
His 4	-	expression tag
His 5	-	expression tag
His 6	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	5
	Total formula weight	53272.1
Non-Polymers*	Number of molecules	3
	Total formula weight	69.0
All*	Total formula weight	53341.0

*Water molecules are not included.