7DCT

Crystal structure of HSF1 DNA-binding domain in complex with 3-site HSE DNA (24 bp)

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D, E... (A, B, C, D, E...)	Heat shock factor protein 1	polymer	113	13214.0	6	UniProt (Q00613) Pfam (PF00447)	Homo sapiens (Human)	HSF 1,Heat shock transcription factor 1,HSTF 1
2	G, I (G, I)	DNA (5'-D(*TP*GP*TP*GP*CP*GP*TP*TP*CP*TP*AP*GP*AP*AP*TP*AP*TP*TP*CP*GP*CP*GP*AP*G)-3')	polymer	24	7415.8	2		Homo sapiens
3	H, J (H, J)	DNA (5'-D(*AP*CP*TP*CP*GP*CP*GP*AP*AP*TP*AP*TP*TP*CP*TP*AP*GP*AP*AP*CP*GP*CP*AP*C)-3')	polymer	24	7322.8	2		Homo sapiens
4	K, L (C, D)	SODIUM ION	non-polymer		23.0	2	Chemie (NA)
5	M, N, O, P, Q... (A, B, C, D, E...)	water	water		18.0	160	Chemie (HOH)

Sequence modifications

A, B, C, D, E, F: 15 - 120 (UniProt: Q00613)

PDB	External Database	Details
Gly 8	-	expression tag
His 9	-	expression tag
His 10	-	expression tag
His 11	-	expression tag
His 12	-	expression tag
His 13	-	expression tag
His 14	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	10
	Total formula weight	108761.2
Non-Polymers*	Number of molecules	2
	Total formula weight	46.0
All*	Total formula weight	108807.2

*Water molecules are not included.