7DAZ
Crystal structure of Drosophila melanogaster Noppera-bo, glutathione S-transferase epsilon 14 (DmGSTE14), in TDP015- and GSH-bound form
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Glutathione S-transferase E14 | polymer | 239 | 27543.8 | 2 | UniProt (Q7JYX0) Pfam (PF02798) Pfam (PF00043) | Drosophila melanogaster (Fruit fly) | Protein noppera-bo |
| 2 | C, F (A, B) | GLUTATHIONE | non-polymer | 307.3 | 2 | Chemie (GSH) | |||
| 3 | D, E, G, H (A, B) | 6-(6,7-dihydro-4H-thieno[3,2-c]pyridin-5-yl)pyridin-3-amine | non-polymer | 231.3 | 4 | Chemie (H29) | |||
| 4 | I, J (A, B) | water | water | 18.0 | 317 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 232 (UniProt: Q7JYX0)
| PDB | External Database | Details |
|---|---|---|
| Met -6 | - | initiating methionine |
| Asn -5 | - | expression tag |
| His -4 | - | expression tag |
| Lys -3 | - | expression tag |
| Val -2 | - | expression tag |
| His -1 | - | expression tag |
| Met 0 | - | expression tag |
| Ile 120 | Thr 120 | variant |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 55087.5 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 1539.9 | |
| All* | Total formula weight | 56627.4 |
