7DAF
IXA in complex with tubulin
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C | Tubulin alpha-1B chain | polymer | 451 | 50204.4 | 2 | UniProt (Q2XVP4) Pfam (PF00091) Pfam (PF03953) In PDB | Sus scrofa (Pig) | Alpha-tubulin ubiquitous,Tubulin K-alpha-1,Tubulin alpha-ubiquitous chain |
| 2 | B, D | Tubulin beta chain | polymer | 445 | 49999.9 | 2 | UniProt (A0A287AGU7) Pfam (PF00091) Pfam (PF03953) UniProt (by SIFTS) (P02554) In PDB | Sus scrofa (Pig) | |
| 3 | E | Stathmin-4 | polymer | 143 | 16844.2 | 1 | UniProt (P63042) Pfam (PF00836) In PDB | Mus musculus (Mouse) | Stathmin-like protein B3,RB3 |
| 4 | F | Tubulin tyrosine ligase | polymer | 384 | 44378.5 | 1 | UniProt (E1BQ43) In PDB | Gallus gallus (Chicken) | |
| 5 | A, C | GUANOSINE-5'-TRIPHOSPHATE | non-polymer | 523.2 | 2 | Chemie (GTP) | |||
| 6 | A, B, C, D, F | MAGNESIUM ION | non-polymer | 24.3 | 6 | Chemie (MG) | |||
| 7 | A, B, C, E | CALCIUM ION | non-polymer | 40.1 | 4 | Chemie (CA) | |||
| 8 | A | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) | |||
| 9 | B, D | GUANOSINE-5'-DIPHOSPHATE | non-polymer | 443.2 | 2 | Chemie (GDP) | |||
| 10 | B | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID | non-polymer | 195.2 | 2 | Chemie (MES) | |||
| 11 | D | (1~{S},3~{S},7~{S},10~{R},11~{S},12~{S},16~{R})-8,8,10,12,16-pentamethyl-3-[(~{E})-1-(2-methyl-1,3-thiazol-4-yl)prop-1-en-2-yl]-7,11-bis(oxidanyl)-17-oxa-4-azabicyclo[14.1.0]heptadecane-5,9-dione | non-polymer | 506.7 | 1 | Chemie (GZX) | |||
| 12 | F | PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER | non-polymer | 505.2 | 1 | Chemie (ACP) | |||
| 13 | water | water | 18.0 | 655 | Chemie (HOH) |
Sequence modifications
E: 5 - 145 (UniProt: P63042)
F: 1 - 378 (UniProt: E1BQ43)
| PDB | External Database | Details |
|---|---|---|
| Met 3 | - | initiating methionine |
| Ala 4 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| His 379 | - | expression tag |
| His 380 | - | expression tag |
| His 381 | - | expression tag |
| His 382 | - | expression tag |
| His 383 | - | expression tag |
| His 384 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 261631.3 | |
| Non-Polymers* | Number of molecules | 19 |
| Total formula weight | 3676.7 | |
| All* | Total formula weight | 265308.1 |
