7D9V

CRTC1 pSer245 peptide in complex with 14-3-3 zeta

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	14-3-3 protein zeta/delta	polymer	265	29948.5	2	UniProt (P63104) Pfam (PF00244)	Homo sapiens (Human)	Protein kinase C inhibitor protein 1,KCIP-1
2	C, D (C, D)	CRTC1 pSer245 peptide	polymer	11	1192.2	2	UniProt (Q6UUV9)	Homo sapiens	CREB-regulated transcription coactivator 1,Mucoepidermoid carcinoma translocated protein 1,Transducer of regulated cAMP response element-binding protein 1,Transducer of CREB protein 1
3	E, F, G (A, B)	GLYCEROL	non-polymer		92.1	3	Chemie (GOL)
4	H, I, J, K (A, B, C, D)	water	water		18.0	218	Chemie (HOH)

Sequence modifications

A, B: 1 - 245 (UniProt: P63104)

PDB	External Database	Details
Met -19	-	initiating methionine
Gly -18	-	expression tag
Ser -17	-	expression tag
Ser -16	-	expression tag
His -15	-	expression tag
His -14	-	expression tag
His -13	-	expression tag
His -12	-	expression tag
His -11	-	expression tag
His -10	-	expression tag
Ser -9	-	expression tag
Ser -8	-	expression tag
Gly -7	-	expression tag
Leu -6	-	expression tag
Val -5	-	expression tag
Pro -4	-	expression tag
Arg -3	-	expression tag
Gly -2	-	expression tag
Ser -1	-	expression tag
His 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	62281.2
Non-Polymers*	Number of molecules	3
	Total formula weight	276.3
All*	Total formula weight	62557.5

*Water molecules are not included.