7D8Z

human potassium-chloride co-transporter KCC2

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (B, A)	potassium-chloride cotransporter 2	polymer	1156	128486.4	2	UniProt (Q9H2X9) Pfam (PF00324) Pfam (PF03522)	Homo sapiens (Human)	Electroneutral potassium-chloride cotransporter 2,K-Cl cotransporter 2,hKCC2,Neuronal K-Cl cotransporter
2	C, D (C, D)	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		424.4	2	In PDB GlyTouCan (G42666HT)
3	E, F, G, H (B, A)	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	4	Chemie (NAG)

Sequence modifications

B, A: 1 - 1139 (UniProt: Q9H2X9)

PDB	External Database	Details
Met -8	-	initiating methionine
Asp -7	-	expression tag
Tyr -6	-	expression tag
Lys -5	-	expression tag
Asp -4	-	expression tag
Asp -3	-	expression tag
Asp -2	-	expression tag
Asp -1	-	expression tag
Lys 0	-	expression tag
Trp 1140	-	expression tag
Ser 1141	-	expression tag
His 1142	-	expression tag
Pro 1143	-	expression tag
Gln 1144	-	expression tag
Phe 1145	-	expression tag
Glu 1146	-	expression tag
Lys 1147	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	256972.8
Branched	Number of molecules	2
	Total formula weight	848.8
Non-Polymers*	Number of molecules	4
	Total formula weight	884.8
All*	Total formula weight	258706.5

*Water molecules are not included.