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7D74

Cryo-EM structure of GMPPA/GMPPB complex bound to GTP (state II)

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C, D
(A, D, B, C)
Mannose-1-phosphate guanyltransferase alphapolymer42046342.04UniProt (Q96IJ6)
Pfam (PF00483)
Pfam (PF00132)
Homo sapiens (Human)GDP-mannose pyrophosphorylase A,GMPP-alpha,GTP-mannose-1-phosphate guanylyltransferase alpha
2E, F, G, H, I...
(E, F, G, H, I...)
Mannose-1-phosphate guanyltransferase betapolymer36039878.38UniProt (Q9Y5P6)
Pfam (PF00483)
Pfam (PF00132)
Homo sapiens (Human)GDP-mannose pyrophosphorylase B,GTP-mannose-1-phosphate guanylyltransferase beta
3M, N, O, P, Q...
(A, D, B, C, E...)
GUANOSINE-5'-TRIPHOSPHATEnon-polymer523.212Chemie (GTP)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains12
Total formula weight504394.4
Non-Polymers*Number of molecules12
Total formula weight6278.2
All*Total formula weight510672.5
*Water molecules are not included.

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PDB entries from 2024-10-30

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