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7D74

Cryo-EM structure of GMPPA/GMPPB complex bound to GTP (state II)

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C, D
(A, D, B, C)
Mannose-1-phosphate guanyltransferase alphapolymer42046342.04UniProt (Q96IJ6)
Pfam (PF00483)
Pfam (PF25087)
Homo sapiens (Human)GDP-mannose pyrophosphorylase A,GMPP-alpha,GTP-mannose-1-phosphate guanylyltransferase alpha
2E, F, G, H, I...
(E, F, G, H, I...)
Mannose-1-phosphate guanyltransferase betapolymer36039878.38UniProt (Q9Y5P6)
Pfam (PF00483)
Pfam (PF25087)
Homo sapiens (Human)GDP-mannose pyrophosphorylase B,GTP-mannose-1-phosphate guanylyltransferase beta
3M, N, O, P, Q...
(A, D, B, C, E...)
GUANOSINE-5'-TRIPHOSPHATEnon-polymer523.212Chemie (GTP)
PubChem (177679032)
PubChem (135400627)
PubChem (135487750)
PubChem (136088935)
PubChem (136803486)
PubChem (135398633)
PubChem (135544356)
PubChem (135547949)
PubChem (135600366)
PubChem (135749822)
PubChem (136005188)
PubChem (136073923)
PubChem (136240914)
PubChem (136664747)
PubChem (136772743)
PubChem (136772744)
PubChem (136803487)
PubChem (137286749)
PubChem (164715984)
PubChem (171699466)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains12
Total formula weight504394.4
Non-Polymers*Number of molecules12
Total formula weight6278.2
All*Total formula weight510672.5
*Water molecules are not included.

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PDB entries from 2026-05-06

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