7D73
Cryo-EM structure of GMPPA/GMPPB complex bound to GTP (State I)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, D, E (A, B, C, D) | Mannose-1-phosphate guanyltransferase alpha | polymer | 420 | 46342.0 | 4 | UniProt (Q96IJ6) Pfam (PF00483) Pfam (PF25087) | Homo sapiens (Human) | GDP-mannose pyrophosphorylase A,GMPP-alpha,GTP-mannose-1-phosphate guanylyltransferase alpha |
| 2 | C, F, G, H, I... (E, F, G, I, J...) | Mannose-1-phosphate guanyltransferase beta | polymer | 360 | 39878.3 | 8 | UniProt (Q9Y5P6) Pfam (PF00483) Pfam (PF25087) | Homo sapiens (Human) | GDP-mannose pyrophosphorylase B,GTP-mannose-1-phosphate guanylyltransferase beta |
| 3 | M, P (A, C) | GUANOSINE-5'-DIPHOSPHATE-ALPHA-D-MANNOSE | non-polymer | 605.3 | 2 | Chemie (GDD) | |||
| 4 | N, O, Q, R, S... (B, E, D, F, G...) | GUANOSINE-5'-TRIPHOSPHATE | non-polymer | 523.2 | 10 | Chemie (GTP) PubChem (177679032) PubChem (135400627) PubChem (135487750) PubChem (136088935) PubChem (136803486) PubChem (135398633) PubChem (135544356) PubChem (135547949) PubChem (135600366) PubChem (135749822) PubChem (136005188) PubChem (136073923) PubChem (136240914) PubChem (136664747) PubChem (136772743) PubChem (136772744) PubChem (136803487) PubChem (137286749) PubChem (164715984) PubChem (171699466) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 12 |
| Total formula weight | 504394.4 | |
| Non-Polymers* | Number of molecules | 12 |
| Total formula weight | 6442.5 | |
| All* | Total formula weight | 510836.9 |
