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7D6G

Neutron crystal Structure of E.coli Dihydrofolate Reductase complexed with folate and NADP+ at pH4.5

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Dihydrofolate reductasepolymer15918019.31UniProt (P0ABQ4)
Pfam (PF00186)
Escherichia coli (strain K12)
2B
(A)
MANGANESE (II) IONnon-polymer54.91Chemie (MN)
3C
(A)
FOLIC ACIDnon-polymer441.41Chemie (FOL)
4D
(A)
NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATEnon-polymer743.41Chemie (NAP)
5E
(A)
waterwater18.0115Chemie (DOD)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight18019.3
Non-Polymers*Number of molecules3
Total formula weight1239.7
All*Total formula weight19259.1
*Water molecules are not included.

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PDB entries from 2025-07-16

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