7D5C
IleRS in complex with a tRNA site inhibitor
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Isoleucine--tRNA ligase, cytoplasmic | polymer | 992 | 114106.9 | 1 | UniProt (P09436) Pfam (PF00133) Pfam (PF08264) Pfam (PF19302) In PDB | Saccharomyces cerevisiae S288c (Baker's yeast) | Isoleucyl-tRNA synthetase,IleRS |
| 2 | A | (2E,4S,5S,6E,8E)-10-[(2S,3R,6S,8R,9S)-3-butyl-9-methyl-2-[(1E,3E)-3-methyl-5-oxidanyl-5-oxidanylidene-penta-1,3-dienyl]-3-(4-oxidanyl-4-oxidanylidene-butanoyl)oxy-1,7-dioxaspiro[5.5]undecan-8-yl]-4,8-dimethyl-5-oxidanyl-deca-2,6,8-trienoic acid | non-polymer | 660.8 | 1 | Chemie (GVU) | |||
| 3 | A | [[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl] (2S,3S)-2-azanyl-3-methyl-pentanoate | non-polymer | 460.4 | 1 | Chemie (GV6) | |||
| 4 | A | 1,2-ETHANEDIOL | non-polymer | 62.1 | 3 | Chemie (EDO) | |||
| 5 | water | water | 18.0 | 673 | Chemie (HOH) |
Sequence modifications
A: 1 - 984 (UniProt: P09436)
| PDB | External Database | Details |
|---|---|---|
| Leu 985 | - | expression tag |
| Glu 986 | - | expression tag |
| His 987 | - | expression tag |
| His 988 | - | expression tag |
| His 989 | - | expression tag |
| His 990 | - | expression tag |
| His 991 | - | expression tag |
| His 992 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 114106.9 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 1307.4 | |
| All* | Total formula weight | 115414.3 |
