7D5C
IleRS in complex with a tRNA site inhibitor
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Isoleucine--tRNA ligase, cytoplasmic | polymer | 992 | 114106.9 | 1 | UniProt (P09436) Pfam (PF00133) Pfam (PF08264) Pfam (PF19302) | Saccharomyces cerevisiae S288c (Baker's yeast) | Isoleucyl-tRNA synthetase,IleRS |
| 2 | B (A) | (2E,4S,5S,6E,8E)-10-[(2S,3R,6S,8R,9S)-3-butyl-9-methyl-2-[(1E,3E)-3-methyl-5-oxidanyl-5-oxidanylidene-penta-1,3-dienyl]-3-(4-oxidanyl-4-oxidanylidene-butanoyl)oxy-1,7-dioxaspiro[5.5]undecan-8-yl]-4,8-dimethyl-5-oxidanyl-deca-2,6,8-trienoic acid | non-polymer | 660.8 | 1 | Chemie (GVU) PubChem (131810) PubChem (6439382) PubChem (9939559) PubChem (177675591) PubChem (44561406) PubChem (101119867) PubChem (124511203) PubChem (56840987) PubChem (124931563) PubChem (125183522) PubChem (9939560) PubChem (162845435) PubChem (91202491) PubChem (101119866) PubChem (101119868) PubChem (124931562) PubChem (124931564) PubChem (125183523) PubChem (125183524) PubChem (129628447) PubChem (133562767) PubChem (162845433) PubChem (162845434) | |||
| 3 | C (A) | [[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl] (2S,3S)-2-azanyl-3-methyl-pentanoate | non-polymer | 460.4 | 1 | Chemie (GV6) PubChem (53636446) | |||
| 4 | D, E, F (A) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 3 | Chemie (EDO) | |||
| 5 | G (A) | water | water | 18.0 | 673 | Chemie (HOH) |
Sequence modifications
A: 1 - 984 (UniProt: P09436)
| PDB | External Database | Details |
|---|---|---|
| Leu 985 | - | expression tag |
| Glu 986 | - | expression tag |
| His 987 | - | expression tag |
| His 988 | - | expression tag |
| His 989 | - | expression tag |
| His 990 | - | expression tag |
| His 991 | - | expression tag |
| His 992 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 114106.9 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 1307.4 | |
| All* | Total formula weight | 115414.3 |
