7D2T

Crystal structure of Rsu1/PINCH1_LIM45C complex

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C	Ras suppressor protein 1	polymer	282	31982.7	2	UniProt (Q15404) Pfam (PF13855) In PDB	Homo sapiens (Human)	Rsu-1
2	B, D	LIM and senescent cell antigen-like-containing domain protein 1	polymer	142	16248.3	2	UniProt (P48059) Pfam (PF00412) In PDB	Homo sapiens (Human)	Particularly interesting new Cys-His protein 1,PINCH-1,Renal carcinoma antigen NY-REN-48
3	A, C	2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL	non-polymer		122.1	2	Chemie (TRS)
4	A, B, C	GLYCEROL	non-polymer		92.1	5	Chemie (GOL)
5	B, D	ZINC ION	non-polymer		65.4	8	Chemie (ZN)
6	B, D	TRIETHYLENE GLYCOL	non-polymer		150.2	2	Chemie (PGE)
7		water	water		18.0	358	Chemie (HOH)

Sequence modifications

A, C: 1 - 277 (UniProt: Q15404)

PDB	External Database	Details
Gly -4	-	expression tag
Ala -3	-	expression tag
Met -2	-	expression tag
Gly -1	-	expression tag
Ser 0	-	expression tag

B, D: 188 - 325 (UniProt: P48059)

PDB	External Database	Details
Gly 184	-	expression tag
Pro 185	-	expression tag
Gly 186	-	expression tag
Ser 187	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	96461.9
Non-Polymers*	Number of molecules	17
	Total formula weight	1528.4
All*	Total formula weight	97990.3

*Water molecules are not included.