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7CZM

Crystal structure of FIP200 Claw/p-OPtineurin LIR complex

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
RB1-inducible coiled-coil protein 1polymer10812403.32UniProt (Q8TDY2)
Pfam (PF10377)
Homo sapiens (Human)FAK family kinase-interacting protein of 200 kDa,FIP200
2C, D
(C, D)
Optineurin LIRpolymer131580.62UniProt (Q96CV9)Homo sapiens (Human)
3E, H
(A, B)
GLYCEROLnon-polymer92.12Chemie (GOL)
4F, G, I, J
(A, B)
CHLORIDE IONnon-polymer35.54Chemie (CL)
5K, L, M, N
(A, B, C, D)
waterwater18.085Chemie (HOH)
Sequence modifications
A, B: 1490 - 1594 (UniProt: Q8TDY2)
PDBExternal DatabaseDetails
Ser 1487-expression tag
Glu 1488-expression tag
Phe 1489-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight27967.8
Non-Polymers*Number of molecules6
Total formula weight326.0
All*Total formula weight28293.8
*Water molecules are not included.

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PDB entries from 2026-01-07

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