7CZF
Crystal structure of Kaposi Sarcoma associated herpesvirus (KSHV ) gHgL in complex with the ligand binding domian (LBD) of EphA2
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, D | Ephrin type-A receptor 2 | polymer | 185 | 21323.1 | 2 | UniProt (P29317) Pfam (PF01404) In PDB | Homo sapiens (Human) | Epithelial cell kinase,Tyrosine-protein kinase receptor ECK |
| 2 | B, E | Envelope glycoprotein H | polymer | 677 | 75374.2 | 2 | UniProt (Q98142) Pfam (PF02489) Pfam (PF17488) In PDB | Human herpesvirus 8 (HHV-8) | gH |
| 3 | C, F | Envelope glycoprotein L | polymer | 157 | 17088.5 | 2 | UniProt (Q76RG7) Pfam (PF11108) In PDB | Human herpesvirus 8 (HHV-8) | gL |
| 4 | L, a, K, N | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 4 | In PDB GlyTouCan (G42666HT) | |||
| 5 | S | alpha-D-mannopyranose-(1-4)-alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-3)][alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 1041.0 | 1 | In PDB GlyTouCan (G73409CU) | |||
| 6 | H | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 570.5 | 1 | In PDB GlyTouCan (G21290RB) | |||
| 7 | B, C, E, F | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 12 | Chemie (NAG) |
Sequence modifications
A, D: 28 - 206 (UniProt: P29317)
C, F: 21 - 167 (UniProt: Q76RG7)
| PDB | External Database | Details |
|---|---|---|
| His 207 | - | expression tag |
| His 208 | - | expression tag |
| His 209 | - | expression tag |
| His 210 | - | expression tag |
| His 211 | - | expression tag |
| His 212 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Asp 17 | - | expression tag |
| Gly 18 | - | expression tag |
| Ile 19 | - | expression tag |
| Gln 20 | - | expression tag |
| His 168 | - | expression tag |
| His 169 | - | expression tag |
| His 170 | - | expression tag |
| His 171 | - | expression tag |
| His 172 | - | expression tag |
| His 173 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 227571.6 | |
| Branched | Number of molecules | 6 |
| Total formula weight | 3309.1 | |
| Non-Polymers* | Number of molecules | 12 |
| Total formula weight | 2654.5 | |
| All* | Total formula weight | 233535.2 |
