7CYL
Crystal structure of Karyopherin-beta2 in complex with FUS PY-NLS(P525L)
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Transportin-1 | polymer | 868 | 98325.4 | 1 | UniProt (Q92973) Pfam (PF03810) Pfam (PF02985) Pfam (PF13513) In PDB | Homo sapiens (Human) | Karyopherin beta-2,Importin beta-2,M9 region interaction protein,MIP |
2 | B | RNA-binding protein FUS | polymer | 54 | 5788.2 | 1 | UniProt (P35637) In PDB | Homo sapiens (Human) | 75 kDa DNA-pairing protein,Oncogene FUS,Oncogene TLS,POMp75,Translocated in liposarcoma protein |
Sequence modifications
A: 1 - 360 (UniProt: Q92973)
A: 368 - 890 (UniProt: Q92973)
B: 476 - 526 (UniProt: P35637)
PDB | External Database | Details |
---|---|---|
Gly -1 | - | expression tag |
Ser 0 | - | expression tag |
PDB | External Database | Details |
---|---|---|
Gly 361 | - | linker |
Gly 362 | - | linker |
Ser 363 | - | linker |
Gly 364 | - | linker |
Gly 365 | - | linker |
Ser 366 | - | linker |
Gly 367 | - | linker |
PDB | External Database | Details |
---|---|---|
Gly 473 | - | expression tag |
Gly 474 | - | expression tag |
Ser 475 | - | expression tag |
Leu 525 | Pro 525 | variant |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 104113.6 | |
All* | Total formula weight | 104113.6 |