7CXK
The ligand-free structure of human PPARgamma LBD R288H mutant in the presence of the SRC-1 coactivator peptide
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Peroxisome proliferator-activated receptor gamma | polymer | 283 | 32261.3 | 1 | UniProt (P37231) Pfam (PF00104) In PDB | Homo sapiens (Human) | PPAR-gamma,Nuclear receptor subfamily 1 group C member 3 |
2 | B | 16-mer peptide from Nuclear receptor coactivator 1 | polymer | 16 | 1905.2 | 1 | UniProt (Q15788) In PDB | Homo sapiens | |
3 | A | MALONATE ION | non-polymer | 102.0 | 1 | Chemie (MLI) | |||
4 | water | water | 18.0 | 77 | Chemie (HOH) |
Sequence modifications
A: 195 - 477 (UniProt: P37231)
PDB | External Database | Details |
---|---|---|
His 288 | Arg 316 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 34166.5 | |
Non-Polymers* | Number of molecules | 1 |
Total formula weight | 102.0 | |
All* | Total formula weight | 34268.5 |