7CXD
Xray structure of rat Galectin-3 CRD in complex with TD-139 belonging to P121 space group
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, D, E) | Galectin-3 | polymer | 146 | 16400.9 | 4 | UniProt (P08699) Pfam (PF00337) | Rattus norvegicus (Rat) | Gal-3,35 kDa lectin,Carbohydrate-binding protein 35,CBP 35,Galactose-specific lectin 3,IgE-binding protein,Laminin-binding protein,Lectin L-29,Mac-2 antigen |
| 2 | E, G, I, J, L (A, B, D, E) | BROMIDE ION | non-polymer | 79.9 | 5 | Chemie (BR) | |||
| 3 | F, H, K, M (A, B, D, E) | 3-deoxy-3-[4-(3-fluorophenyl)-1H-1,2,3-triazol-1-yl]-beta-D-galactopyranosyl 3-deoxy-3-[4-(3-fluorophenyl)-1H-1,2,3-triazol-1-yl]-1-thio-beta-D-galactopyranoside | non-polymer | 648.6 | 4 | Chemie (TD2) | |||
| 4 | N, O, P, Q (A, B, D, E) | water | water | 18.0 | 266 | Chemie (HOH) |
Sequence modifications
A, B, D, E: 120 - 262 (UniProt: P08699)
| PDB | External Database | Details |
|---|---|---|
| Gly 117 | - | expression tag |
| His 118 | - | expression tag |
| Met 119 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 65603.5 | |
| Non-Polymers* | Number of molecules | 9 |
| Total formula weight | 2994.1 | |
| All* | Total formula weight | 68597.6 |
