7CXD
Xray structure of rat Galectin-3 CRD in complex with TD-139 belonging to P121 space group
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, D, E) | Galectin-3 | polymer | 146 | 16400.9 | 4 | UniProt (P08699) Pfam (PF00337) | Rattus norvegicus (Rat) | Gal-3,35 kDa lectin,Carbohydrate-binding protein 35,CBP 35,Galactose-specific lectin 3,IgE-binding protein,Laminin-binding protein,Lectin L-29,Mac-2 antigen |
| 2 | E, G, I, J, L (A, B, D, E) | BROMIDE ION | non-polymer | 79.9 | 5 | Chemie (BR) PubChem (259) | |||
| 3 | F, H, K, M (A, B, D, E) | 3-deoxy-3-[4-(3-fluorophenyl)-1H-1,2,3-triazol-1-yl]-beta-D-galactopyranosyl 3-deoxy-3-[4-(3-fluorophenyl)-1H-1,2,3-triazol-1-yl]-1-thio-beta-D-galactopyranoside | non-polymer | 648.6 | 4 | Chemie (TD2) PubChem (73774610) PubChem (90109156) PubChem (118436792) PubChem (118679947) PubChem (118657353) PubChem (122418481) PubChem (126624445) PubChem (126624423) PubChem (130471368) PubChem (118404248) PubChem (118408645) PubChem (118507865) PubChem (134692124) PubChem (118680035) PubChem (126624426) PubChem (129261745) PubChem (140639477) PubChem (140820580) PubChem (145121529) PubChem (153447831) PubChem (173976503) PubChem (173733738) PubChem (173742413) | |||
| 4 | N, O, P, Q (A, B, D, E) | water | water | 18.0 | 266 | Chemie (HOH) |
Sequence modifications
A, B, D, E: 120 - 262 (UniProt: P08699)
| PDB | External Database | Details |
|---|---|---|
| Gly 117 | - | expression tag |
| His 118 | - | expression tag |
| Met 119 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 65603.5 | |
| Non-Polymers* | Number of molecules | 9 |
| Total formula weight | 2994.1 | |
| All* | Total formula weight | 68597.6 |
