7CWZ
Crystal structure of a tyrosine decarboxylase from Enterococcus faecalis K392A mutant in complex with the cofactor PLP and L-dopa
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C (A, B, C) | Decarboxylase | polymer | 620 | 70075.9 | 3 | UniProt (Q8KXD2) Pfam (PF00282) Pfam (PF21391) UniProt (by SIFTS) (Q838D6) | Enterococcus faecalis | Tyrosine decarboxylase |
| 2 | D, G (A, B) | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) | |||
| 3 | E, H, J (A, B, C) | PYRIDOXAL-5'-PHOSPHATE | non-polymer | 247.1 | 3 | Chemie (PLP) | |||
| 4 | F, I, K (A, B, C) | L-DOPAMINE | non-polymer | 153.2 | 3 | Chemie (LDP) | |||
| 5 | L, M, N (A, B, C) | water | water | 18.0 | 56 | Chemie (HOH) |
Sequence modifications
A, B, C: 1 - 620 (UniProt: Q8KXD2)
| PDB | External Database | Details |
|---|---|---|
| Lys 62 | Glu 62 | conflict |
| Ala 392 | Lys 392 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 210227.6 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 1249.6 | |
| All* | Total formula weight | 211477.2 |
