7CWF
Crystal structure of PDE8A catalytic domain in complex with 2c
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A | polymer | 338 | 39090.0 | 1 | UniProt (O60658) Pfam (PF00233) In PDB | Homo sapiens (Human) | |
| 2 | A | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
| 3 | A | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
| 4 | A | 9-[[4-[2,2-bis(fluoranyl)ethoxy]pyridin-2-yl]methyl]-2-chloranyl-purin-6-amine | non-polymer | 340.7 | 1 | Chemie (GJR) | |||
| 5 | water | water | 18.0 | 52 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 39090.0 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 430.4 | |
| All* | Total formula weight | 39520.4 |
