7CVS
Crystal structure of the C85A/L194A mutant CLC-ec1 with Fab fragment
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | H(+)/Cl(-) exchange transporter ClcA | polymer | 473 | 50316.3 | 2 | UniProt (D7XDR7) Pfam (PF00654) UniProt (by SIFTS) (P37019) In PDB | Escherichia coli MS 198-1 | |
2 | C, E | antibody Fab fragment heavy chain | polymer | 222 | 23823.0 | 2 | Mus musculus | ||
3 | D, F | antibody Fab fragment light chain | polymer | 211 | 23088.4 | 2 | Mus musculus | ||
4 | A, B | CHLORIDE ION | non-polymer | 35.5 | 4 | Chemie (CL) |
Sequence modifications
A, B: 1 - 473 (UniProt: D7XDR7)
PDB | External Database | Details |
---|---|---|
Ala 85 | Cys 85 | engineered mutation |
Ala 194 | Leu 194 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 6 |
Total formula weight | 194455.5 | |
Non-Polymers* | Number of molecules | 4 |
Total formula weight | 141.8 | |
All* | Total formula weight | 194597.3 |