7CVP

The Crystal Structure of human PHGDH from Biortus.

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	D-3-phosphoglycerate dehydrogenase	polymer	329	35425.6	2	UniProt (O43175) Pfam (PF00389) Pfam (PF02826)	Homo sapiens (Human)	3-PGDH,2-oxoglutarate reductase,Malate dehydrogenase
2	C, D (A, B)	NICOTINAMIDE-ADENINE-DINUCLEOTIDE	non-polymer		663.4	2	Chemie (NAD)
3	E, F (A, B)	water	water		18.0	16	Chemie (HOH)

Sequence modifications

A, B: 4 - 315 (UniProt: O43175)

PDB	External Database	Details
Met -13	-	expression tag
Gly -12	-	expression tag
Gly -11	-	expression tag
Ser -10	-	expression tag
His -9	-	expression tag
His -8	-	expression tag
His -7	-	expression tag
His -6	-	expression tag
His -5	-	expression tag
His -4	-	expression tag
Glu -3	-	expression tag
Asn -2	-	expression tag
Leu -1	-	expression tag
Tyr 0	-	expression tag
Phe 1	-	expression tag
Gln 2	-	expression tag
Gly 3	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	70851.3
Non-Polymers*	Number of molecules	2
	Total formula weight	1326.8
All*	Total formula weight	72178.1

*Water molecules are not included.