7CVN
The N-arylsulfonyl-indole-2-carboxamide-based inhibitors against fructose-1,6-bisphosphatase
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Fructose-1,6-bisphosphatase 1 | polymer | 338 | 36887.4 | 4 | UniProt (P09467) Pfam (PF00316) Pfam (PF18913) | Homo sapiens (Human) | FBPase 1,D-fructose-1,6-bisphosphate 1-phosphohydrolase 1,Liver FBPase |
| 2 | E, G, I, K (A, B, C, D) | 4-(3-acetamidophenyl)-N-(4-methoxyphenyl)sulfonyl-7-nitro-1H-indole-2-carboxamide | non-polymer | 508.5 | 4 | Chemie (GJO) | |||
| 3 | F, H, J, L (A, B, C, D) | 1,6-di-O-phosphono-beta-D-fructofuranose | non-polymer | 340.1 | 4 | Chemie (FBP) PubChem (718) PubChem (10267) PubChem (172313) PubChem (440117) PubChem (5702629) PubChem (12800340) PubChem (16219368) PubChem (24802138) PubChem (46937007) PubChem (445557) PubChem (92209487) PubChem (124383956) PubChem (124540446) PubChem (135053794) PubChem (89534552) PubChem (92209485) PubChem (92209486) PubChem (123134048) PubChem (124202619) PubChem (124427861) PubChem (124524513) PubChem (124604817) PubChem (130233858) PubChem (133126640) PubChem (135055131) PubChem (140434362) PubChem (146159004) PubChem (160510795) | |||
| 4 | M, N, O, P (A, B, C, D) | water | water | 18.0 | 327 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 147549.7 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 3394.5 | |
| All* | Total formula weight | 150944.2 |
