7CTY
Wild type plasmodium falciparum dihydrofolate reductase-thymidylate synthase (PfDHFR-TS), fragment 263, NADP+, dUMP
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Bifunctional dihydrofolate reductase-thymidylate synthase | polymer | 608 | 71828.0 | 2 | UniProt (A7UD81) Pfam (PF00186) Pfam (PF00303) UniProt (by SIFTS) (Q8I1R6) | Plasmodium falciparum (malaria parasite P. falciparum) | |
| 2 | C (A) | NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | non-polymer | 745.4 | 1 | Chemie (NDP) | |||
| 3 | D, G (A, B) | spiro[1H-2-benzofuran-3,4'-piperidine] | non-polymer | 189.3 | 2 | Chemie (GF3) | |||
| 4 | E, F (A, B) | PHOSPHATE ION | non-polymer | 95.0 | 2 | Chemie (PO4) | |||
| 5 | H, I (A, B) | water | water | 18.0 | 16 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 143656.0 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 1313.9 | |
| All* | Total formula weight | 144969.9 |
