7CTW
Wild-type Plasmodium falciparum dihydrofolate reductase-thymidylate synthase (PfDHFR-TS) complexed with fragment 820, NADPH, dUMP
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | Bifunctional dihydrofolate reductase-thymidylate synthase | polymer | 608 | 71828.0 | 2 | UniProt (A7UD81) Pfam (PF00186) Pfam (PF00303) UniProt (by SIFTS) (P13922) In PDB | Plasmodium falciparum (malaria parasite P. falciparum) | |
| 2 | A, B | NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | non-polymer | 745.4 | 2 | Chemie (NDP) | |||
| 3 | A | 1-(2-methylsulfanylphenyl)piperazine | non-polymer | 208.3 | 1 | Chemie (GEX) | |||
| 4 | A | PHOSPHATE ION | non-polymer | 95.0 | 1 | Chemie (PO4) | |||
| 5 | water | water | 18.0 | 65 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 143656.0 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 1794.1 | |
| All* | Total formula weight | 145450.1 |
