7CTC
FECH - inhibitor complex 1
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, D) | Ferrochelatase, mitochondrial | polymer | 423 | 47881.1 | 2 | UniProt (P22830) Pfam (PF00762) | Homo sapiens (Human) | Heme synthase,Protoheme ferro-lyase |
| 2 | C, E (A, D) | FE2/S2 (INORGANIC) CLUSTER | non-polymer | 175.8 | 2 | Chemie (FES) | |||
| 3 | D, F (A, D) | 2-(4-tert-butylphenyl)-5-[(quinolin-2-ylamino)methyl]-6H-[1,2,4]triazolo[1,5-a]pyrimidin-7-one | non-polymer | 424.5 | 2 | Chemie (GFO) | |||
| 4 | G, H (A, D) | water | water | 18.0 | 434 | Chemie (HOH) |
Sequence modifications
A, D: 1 - 423 (UniProt: P22830)
| PDB | External Database | Details |
|---|---|---|
| Leu 115 | Arg 115 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 95762.1 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 1200.6 | |
| All* | Total formula weight | 96962.8 |
