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7CRU

hnRNPK NLS in complex with Importin alpha 1 (KPNA2)

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, C
(B, D)
Heterogeneous nuclear ribonucleoprotein Kpolymer232877.22UniProt (P61978)
Pfam (PF08067)
Homo sapiens (Human)hnRNPK NLS, hnRNP K,Transformation up-regulated nuclear protein,TUNP
2B, D
(A, C)
Importin subunit alpha-1polymer45749520.22UniProt (P52292)
Pfam (PF00514)
Pfam (PF16186)
Homo sapiens (Human)Karyopherin subunit alpha-2,RAG cohort protein 1,SRP1-alpha
3E, F, H, I, J
(A, D, C)
ACETATE IONnon-polymer59.05Chemie (ACT)
PubChem (175)
4G
(C)
GLYCEROLnon-polymer92.11Chemie (GOL)
PubChem (753)
5K, L, M, N
(B, A, D, C)
waterwater18.097Chemie (HOH)
Sequence modifications
B, D: 18 - 38 (UniProt: P61978)
PDBExternal DatabaseDetails
Trp 16-expression tag
Met 17-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight104794.8
Non-Polymers*Number of molecules6
Total formula weight387.3
All*Total formula weight105182.1
*Water molecules are not included.

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PDB entries from 2026-04-08

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