7CRU

hnRNPK NLS in complex with Importin alpha 1 (KPNA2)

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005737	cellular_component	cytoplasm
A	0006606	biological_process	protein import into nucleus
A	0061608	molecular_function	nuclear import signal receptor activity
C	0005737	cellular_component	cytoplasm
C	0006606	biological_process	protein import into nucleus
C	0061608	molecular_function	nuclear import signal receptor activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	2
Details	binding site for residue ACT A 601

Chain	Residue
A	GLU180
B	ARG37

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site_id	AC2
Number of Residues	2
Details	binding site for residue ACT D 101

Chain	Residue
C	GLU180
D	ARG37

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site_id	AC3
Number of Residues	3
Details	binding site for residue GOL C 601

Chain	Residue
C	GLN371
C	THR409
C	GLU411

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site_id	AC4
Number of Residues	3
Details	binding site for residue ACT C 602

Chain	Residue
C	ASN346
C	ALA304
C	SER305

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site_id	AC5
Number of Residues	5
Details	binding site for residue ACT C 603

Chain	Residue
C	LYS353
C	GLU354
C	TRP357
C	GLU396
D	GLU25

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site_id	AC6
Number of Residues	1
Details	binding site for residue ACT C 604

Chain	Residue
C	ASP270

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	2
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:18669648, ECO:0007744|PubMed:20068231, ECO:0007744|PubMed:23186163

Chain	Residue	Details
C	SER490
A	SER490

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site_id	SWS_FT_FI2
Number of Residues	2
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:23186163

Chain	Residue	Details
D	SER36
B	SER36

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site_id	SWS_FT_FI3
Number of Residues	4
Details	CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2); alternate => ECO:0007744|PubMed:25114211, ECO:0007744|PubMed:25218447, ECO:0007744|PubMed:28112733

Chain	Residue	Details
D	LYS34
B	LYS34

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