7CQE

Crystal structure of the catalytic domain of the proto-oncogene tyrosine-protein kinase MER in complex with AZD-7762

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, C)	Tyrosine-protein kinase Mer	polymer	294	33856.2	2	UniProt (Q12866) Pfam (PF07714)	Homo sapiens (Human)	Proto-oncogene c-Mer,Receptor tyrosine kinase MerTK
2	C, D, E, F, G... (A, C)	CHLORIDE ION	non-polymer		35.5	6	Chemie (CL)
3	H, J (A, C)	5-(3-fluorophenyl)-N-[(3S)-3-piperidyl]-3-ureido-thiophene-2-carboxamide	non-polymer		362.4	2	Chemie (YDJ)
4	K, L (A, C)	water	water		18.0	20	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	67712.5
Non-Polymers*	Number of molecules	8
	Total formula weight	937.6
All*	Total formula weight	68650.0

*Water molecules are not included.