7CPY

Lovastatin nonaketide synthase with LovC

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (C, D)	Lovastatin nonaketide synthase, enoyl reductase component lovC	polymer	371	40622.9	2	UniProt (Q9Y7D0)	Aspergillus terreus	Lovastatin biosynthesis cluster protein C,Trans-enoyl reductase lovC
2	C, D (A, B)	Lovastatin nonaketide synthase, polyketide synthase component	polymer	3046	336446.7	2	UniProt (Q9Y8A5)	Aspergillus terreus	LNKS,Lovastatin biosynthesis cluster protein B
3	E, F (A, B)	NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE	non-polymer		743.4	2	Chemie (NAP)

Sequence modifications

C, D: 1 - 363 (UniProt: Q9Y7D0)

PDB	External Database	Details
Leu 364	-	expression tag
Glu 365	-	expression tag
His 366	-	expression tag
His 367	-	expression tag
His 368	-	expression tag
His 369	-	expression tag
His 370	-	expression tag
His 371	-	expression tag

A, B: 1 - 3038 (UniProt: Q9Y8A5)

PDB	External Database	Details
Gln 1884	Gly 1884	engineered mutation
Ala 1885	Gln 1885	engineered mutation
His 3039	-	expression tag
Val 3040	-	expression tag
His 3041	-	expression tag
His 3042	-	expression tag
His 3043	-	expression tag
His 3044	-	expression tag
His 3045	-	expression tag
His 3046	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	754139.1
Non-Polymers*	Number of molecules	2
	Total formula weight	1486.8
All*	Total formula weight	755625.9

*Water molecules are not included.