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7COD

Post insertion complex of DNA polymerase Mu (K438A/Q441A) with 1-nt gapped DNA

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1ADNA-directed DNA/RNA polymerase mupolymer48253681.01UniProt (Q9NP87)
Pfam (PF14716)
Pfam (PF10391)
Pfam (PF14792)
Pfam (PF14791)
In PDB
Homo sapiens (Human)Pol Mu,Terminal transferase
2TDNA (5'-D(*CP*GP*GP*CP*TP*TP*AP*CP*G)-3')polymer92731.81synthetic construct
3PDNA (5'-D(*CP*GP*TP*AP*G)-3')polymer51520.01synthetic construct
4DDNA (5'-D(P*GP*CP*CP*G)-3')polymer41191.81synthetic construct
5AGLYCEROLnon-polymer92.11Chemie (GOL)
6A2'-DEOXYGUANOSINE-5'-TRIPHOSPHATEnon-polymer507.21Chemie (DGT)
7A, PMAGNESIUM IONnon-polymer24.33Chemie (MG)
8ASODIUM IONnon-polymer23.01Chemie (NA)
9waterwater18.0348Chemie (HOH)
Sequence modifications
A: 1 - 494 (UniProt: Q9NP87)
PDBExternal DatabaseDetails
-Pro 398deletion
-Gly 399deletion
-Ala 400deletion
-Ala 401deletion
-Val 402deletion
-Gly 403deletion
-Gly 404deletion
-Ser 405deletion
-Thr 406deletion
-Arg 407deletion
-Pro 408deletion
-Cys 409deletion
Gly 410Pro 410engineered mutation
Ala 438Lys 438engineered mutation
Ala 441Gln 441engineered mutation
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight59124.7
Non-Polymers*Number of molecules6
Total formula weight695.2
All*Total formula weight59819.8
*Water molecules are not included.

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PDB entries from 2024-06-12

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