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7COB

Ternary complex of DNA polymerase Mu (Q441A) with 1-nt gapped DNA (T:dGMPNPP)

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1ADNA-directed DNA/RNA polymerase mupolymer48253739.11UniProt (Q9NP87)
Pfam (PF14716)
Pfam (PF10391)
Pfam (PF14792)
Pfam (PF14791)
In PDB
Homo sapiens (Human)Pol Mu,Terminal transferase
2TDNA (5'-D(*CP*GP*GP*CP*TP*TP*AP*CP*G)-3')polymer92731.81synthetic construct
3PDNA (5'-D(*CP*GP*TP*A)-3')polymer41190.81synthetic construct
4DDNA (5'-D(P*GP*CP*CP*G)-3')polymer41191.81synthetic construct
5A2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]guanosinenon-polymer506.21Chemie (XG4)
6A, TMAGNESIUM IONnon-polymer24.33Chemie (MG)
7waterwater18.0237Chemie (HOH)
Sequence modifications
A: 1 - 494 (UniProt: Q9NP87)
PDBExternal DatabaseDetails
-Pro 398deletion
-Gly 399deletion
-Ala 400deletion
-Ala 401deletion
-Val 402deletion
-Gly 403deletion
-Gly 404deletion
-Ser 405deletion
-Thr 406deletion
-Arg 407deletion
-Pro 408deletion
-Cys 409deletion
Gly 410Pro 410engineered mutation
Ala 441Gln 441engineered mutation
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight58853.6
Non-Polymers*Number of molecules4
Total formula weight579.1
All*Total formula weight59432.7
*Water molecules are not included.

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PDB entries from 2024-06-12

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