7CNL
Crystal structure of TEAD3 in complex with VT105
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D | Transcriptional enhancer factor TEF-5 | polymer | 221 | 25365.8 | 4 | UniProt (Q99594) Pfam (PF17725) In PDB | Homo sapiens (Human) | DTEF-1,TEA domain family member 3,TEAD-3 |
| 2 | A, C | N-oxidanyltetradecanamide | non-polymer | 243.4 | 2 | Chemie (G9O) | |||
| 3 | A, B, C, D | PHOSPHATE ION | non-polymer | 95.0 | 8 | Chemie (PO4) | |||
| 4 | A, B | CHLORIDE ION | non-polymer | 35.5 | 4 | Chemie (CL) | |||
| 5 | B, D | N-[(1S)-1-pyridin-2-ylethyl]-8-[4-(trifluoromethyl)phenyl]quinoline-3-carboxamide | non-polymer | 421.4 | 2 | Chemie (G9C) | |||
| 6 | C | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL | non-polymer | 122.1 | 1 | Chemie (TRS) | |||
| 7 | water | water | 18.0 | 34 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 216 - 435 (UniProt: Q99594)
| PDB | External Database | Details |
|---|---|---|
| Gly 215 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 101463.4 | |
| Non-Polymers* | Number of molecules | 17 |
| Total formula weight | 2353.3 | |
| All* | Total formula weight | 103816.7 |
