7CL0
Crystal structure of human SIRT6
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | NAD-dependent protein deacetylase sirtuin-6 | polymer | 355 | 39180.9 | 1 | UniProt (Q8N6T7) Pfam (PF02146) | Homo sapiens (Human) | Regulatory protein SIR2 homolog 6,SIR2-like protein 6 |
| 2 | B (D) | THR-ALA-ARG-LYS-SER-THR-GLY | polymer | 9 | 907.0 | 1 | Homo sapiens (Human) | ||
| 3 | C (A) | [(2R,3S,4R,5R)-5-(6-AMINOPURIN-9-YL)-3,4-DIHYDROXY-OXOLAN-2-YL]METHYL [HYDROXY-[[(2R,3S,4R,5S)-3,4,5-TRIHYDROXYOXOLAN-2-YL]METHOXY]PHOSPHORYL] HYDROGEN PHOSPHATE | non-polymer | 559.3 | 1 | Chemie (AR6) | |||
| 4 | D (A) | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
| 5 | E, F, G, H, I... (A) | SULFATE ION | non-polymer | 96.1 | 8 | Chemie (SO4) | |||
| 6 | M, N, O, P, Q... (A) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 8 | Chemie (EDO) | |||
| 7 | U (D) | tetradecanethial | non-polymer | 228.4 | 1 | Chemie (G4U) | |||
| 8 | V (D) | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 1 | Chemie (PEG) | |||
| 9 | W, X (A, D) | water | water | 18.0 | 234 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 40087.9 | |
| Non-Polymers* | Number of molecules | 20 |
| Total formula weight | 2224.3 | |
| All* | Total formula weight | 42312.2 |
