7CKI
Crystal structure of Tryptophanyl-tRNA synthetase from Bacillus stearothermophilus in complex with chuangxinmycin and ATP
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Tryptophan--tRNA ligase | polymer | 330 | 37467.9 | 1 | UniProt (P00953) Pfam (PF00579) | Geobacillus stearothermophilus | Tryptophanyl-tRNA synthetase,TrpRS |
| 2 | B (A) | (5~{S},6~{R})-5-methyl-7-thia-2-azatricyclo[6.3.1.0^{4,12}]dodeca-1(12),3,8,10-tetraene-6-carboxylic acid | non-polymer | 233.3 | 1 | Chemie (9E0) | |||
| 3 | C (A) | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
| 4 | D, F, G (A) | POTASSIUM ION | non-polymer | 39.1 | 3 | Chemie (K) | |||
| 5 | E (A) | ADENOSINE-5'-TRIPHOSPHATE | non-polymer | 507.2 | 1 | Chemie (ATP) | |||
| 6 | H (A) | water | water | 18.0 | 159 | Chemie (HOH) |
Sequence modifications
A: 1 - 328 (UniProt: P00953)
| PDB | External Database | Details |
|---|---|---|
| Leu 64 | Lys 64 | engineered mutation |
| Leu 329 | - | expression tag |
| Glu 330 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 37467.9 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 882.1 | |
| All* | Total formula weight | 38350.0 |
