7CI5
Crystal structure of P.aeruginosa LpxC in complex with inhibitor
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | UDP-3-O-acyl-N-acetylglucosamine deacetylase | polymer | 299 | 33146.6 | 4 | UniProt (P47205) Pfam (PF03331) | Pseudomonas aeruginosa PAO1 | UDP-3-O-acyl-GlcNAc deacetylase,UDP-3-O-[R-3-hydroxymyristoyl]-N-acetylglucosamine deacetylase |
| 2 | E, H, K, N (A, B, C, D) | (3R)-3-azanyl-4-oxidanylidene-4-[[3-(trifluoromethyloxy)phenyl]amino]butanoic acid | non-polymer | 292.2 | 4 | Chemie (FXX) | |||
| 3 | F, I, L, O (A, B, C, D) | 3[N-MORPHOLINO]PROPANE SULFONIC ACID | non-polymer | 209.3 | 4 | Chemie (MPO) | |||
| 4 | G, J, M, P (A, B, C, D) | ZINC ION | non-polymer | 65.4 | 4 | Chemie (ZN) | |||
| 5 | Q, R, S, T (A, B, C, D) | water | water | 18.0 | 178 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 1 - 299 (UniProt: P47205)
| PDB | External Database | Details |
|---|---|---|
| Ser 40 | Cys 40 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 132586.5 | |
| Non-Polymers* | Number of molecules | 12 |
| Total formula weight | 2267.5 | |
| All* | Total formula weight | 134854.0 |
