7CI4
Crystal structure of P.aeruginosa LpxC in complex with inhibitor
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | UDP-3-O-acyl-N-acetylglucosamine deacetylase | polymer | 299 | 33146.6 | 2 | UniProt (P47205) Pfam (PF03331) | Pseudomonas aeruginosa PAO1 | UDP-3-O-acyl-GlcNAc deacetylase,UDP-3-O-[R-3-hydroxymyristoyl]-N-acetylglucosamine deacetylase |
| 2 | C, G (A, B) | (2R)-2-azanyl-4-methylsulfonyl-N-[3-(trifluoromethyloxy)phenyl]butanamide | non-polymer | 340.3 | 2 | Chemie (FXU) | |||
| 3 | D, H (A, B) | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
| 4 | E, I (A, B) | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) | |||
| 5 | F, J (A, B) | CHLORIDE ION | non-polymer | 35.5 | 2 | Chemie (CL) | |||
| 6 | K, L (A, B) | water | water | 18.0 | 361 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 299 (UniProt: P47205)
| PDB | External Database | Details |
|---|---|---|
| Ser 40 | Cys 40 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 66293.2 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 931.0 | |
| All* | Total formula weight | 67224.2 |
