7CDE
Crystal structure of LSD1-CoREST in complex with PRSFLVRKR peptide
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Lysine-specific histone demethylase 1A | polymer | 669 | 74333.0 | 1 | UniProt (O60341) Pfam (PF04433) Pfam (PF01593) In PDB | Homo sapiens (Human) | BRAF35-HDAC complex protein BHC110,Flavin-containing amine oxidase domain-containing protein 2 |
2 | B | REST corepressor 1 | polymer | 140 | 15850.9 | 1 | UniProt (Q9UKL0) Pfam (PF20878) Pfam (PF00249) In PDB | Homo sapiens (Human) | Protein CoREST |
3 | C | PRO-ARG-SER-PHE-LEU-VAL-ARG-LYS-ARG | polymer | 9 | 1162.4 | 1 | Homo sapiens | ||
4 | A | FLAVIN-ADENINE DINUCLEOTIDE | non-polymer | 785.5 | 1 | Chemie (FAD) | |||
5 | A | GLYCEROL | non-polymer | 92.1 | 5 | Chemie (GOL) | |||
6 | water | water | 18.0 | 63 | Chemie (HOH) |
Sequence modifications
A: 172 - 833 (UniProt: O60341)
B: 308 - 440 (UniProt: Q9UKL0)
PDB | External Database | Details |
---|---|---|
Gly 165 | - | expression tag |
Pro 166 | - | expression tag |
Leu 167 | - | expression tag |
Gly 168 | - | expression tag |
Ser 169 | - | expression tag |
His 170 | - | expression tag |
Met 171 | - | expression tag |
PDB | External Database | Details |
---|---|---|
Gly 301 | - | expression tag |
Ser 302 | - | expression tag |
Ser 303 | - | expression tag |
Gly 304 | - | expression tag |
Ser 305 | - | expression tag |
Ala 306 | - | expression tag |
Ser 307 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 3 |
Total formula weight | 91346.4 | |
Non-Polymers* | Number of molecules | 6 |
Total formula weight | 1246.0 | |
All* | Total formula weight | 92592.4 |