7CCY
Crystal structure of the 2-iodoporphobilinogen-bound holo form of human hydroxymethylbilane synthase
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, C) | Porphobilinogen deaminase | polymer | 361 | 39383.0 | 2 | UniProt (P08397) Pfam (PF01379) Pfam (PF03900) | Homo sapiens (Human) | PBG-D,Hydroxymethylbilane synthase,HMBS,Pre-uroporphyrinogen synthase |
| 2 | C, E (A, C) | 3-[5-{[3-(2-carboxyethyl)-4-(carboxymethyl)-5-methyl-1H-pyrrol-2-yl]methyl}-4-(carboxymethyl)-1H-pyrrol-3-yl]propanoic acid | non-polymer | 420.4 | 2 | Chemie (DPM) | |||
| 3 | D (C) | 3-[5-(aminomethyl)-4-(carboxymethyl)-2-iodo-1H-pyrrol-3-yl]propanoic acid | non-polymer | 352.1 | 1 | Chemie (FWL) | |||
| 4 | F, G (A, C) | water | water | 18.0 | 64 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 78766.0 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 1193.0 | |
| All* | Total formula weight | 79959.0 |
