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7CCY

Crystal structure of the 2-iodoporphobilinogen-bound holo form of human hydroxymethylbilane synthase

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, CPorphobilinogen deaminasepolymer36139383.02UniProt (P08397)
Pfam (PF01379)
Pfam (PF03900)
In PDB
Homo sapiens (Human)PBG-D,Hydroxymethylbilane synthase,HMBS,Pre-uroporphyrinogen synthase
2A, C3-[5-{[3-(2-carboxyethyl)-4-(carboxymethyl)-5-methyl-1H-pyrrol-2-yl]methyl}-4-(carboxymethyl)-1H-pyrrol-3-yl]propanoic acidnon-polymer420.42Chemie (DPM)
3C3-[5-(aminomethyl)-4-(carboxymethyl)-2-iodo-1H-pyrrol-3-yl]propanoic acidnon-polymer352.11Chemie (FWL)
4waterwater18.064Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight78766.0
Non-Polymers*Number of molecules3
Total formula weight1193.0
All*Total formula weight79959.0
*Water molecules are not included.

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PDB entries from 2024-07-10

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