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7CCX

Crystal structure of the holo form of human hydroxymethylbilane synthase

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, C)
Porphobilinogen deaminasepolymer36139383.02UniProt (P08397)
Pfam (PF01379)
Pfam (PF03900)
Homo sapiens (Human)PBG-D,Hydroxymethylbilane synthase,HMBS,Pre-uroporphyrinogen synthase
2C, D
(A, C)
3-[5-{[3-(2-carboxyethyl)-4-(carboxymethyl)-5-methyl-1H-pyrrol-2-yl]methyl}-4-(carboxymethyl)-1H-pyrrol-3-yl]propanoic acidnon-polymer420.42Chemie (DPM)
3E, F
(A, C)
waterwater18.0159Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight78766.0
Non-Polymers*Number of molecules2
Total formula weight840.8
All*Total formula weight79606.9
*Water molecules are not included.

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PDB entries from 2024-11-13

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