7CBZ
Crystal structure of T2R-TTL-A31 complex
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, C | Tubulin alpha-1B chain | polymer | 451 | 50204.4 | 2 | UniProt (Q2XVP4) Pfam (PF00091) Pfam (PF03953) In PDB | Sus scrofa (Pig) | Alpha-tubulin ubiquitous,Tubulin K-alpha-1,Tubulin alpha-ubiquitous chain |
2 | B, D | Tubulin beta chain | polymer | 445 | 49999.9 | 2 | UniProt (P02554) Pfam (PF00091) Pfam (PF03953) In PDB | Sus scrofa (Pig) | Beta-tubulin |
3 | E | Stathmin-4 | polymer | 189 | 22125.3 | 1 | UniProt (P63043) Pfam (PF00836) In PDB | Rattus norvegicus (Rat) | Stathmin-like protein B3,RB3 |
4 | F | Tubulin tyrosine ligase | polymer | 383 | 44240.4 | 1 | UniProt (E1BQ43) In PDB | Gallus gallus (Chicken) | |
5 | A, C | GUANOSINE-5'-TRIPHOSPHATE | non-polymer | 523.2 | 2 | Chemie (GTP) | |||
6 | A, B, C, D, F | MAGNESIUM ION | non-polymer | 24.3 | 5 | Chemie (MG) | |||
7 | A, B, C, D | CALCIUM ION | non-polymer | 40.1 | 6 | Chemie (CA) | |||
8 | B, D | 2-[5-[4-[2-[4-(2-cyclopropylethanoyl)piperazin-1-yl]ethoxy]phenyl]pyridin-2-yl]-N-(phenylmethyl)ethanamide | non-polymer | 512.6 | 2 | Chemie (FUO) | |||
9 | B | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID | non-polymer | 195.2 | 1 | Chemie (MES) | |||
10 | B, D | GUANOSINE-5'-DIPHOSPHATE | non-polymer | 443.2 | 2 | Chemie (GDP) | |||
11 | water | water | 18.0 | 116 | Chemie (HOH) |
Sequence modifications
B, D: 1 - 447 (UniProt: P02554)
F: 1 - 378 (UniProt: E1BQ43)
PDB | External Database | Details |
---|---|---|
Thr 57 | Ala 55 | conflict |
Met 172 | Val 170 | conflict |
Ser 298 | Ala 296 | conflict |
Ile 318 | Val 316 | conflict |
PDB | External Database | Details |
---|---|---|
His 379 | - | expression tag |
His 380 | - | expression tag |
His 381 | - | expression tag |
His 382 | - | expression tag |
His 383 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 6 |
Total formula weight | 266774.3 | |
Non-Polymers* | Number of molecules | 18 |
Total formula weight | 3515.3 | |
All* | Total formula weight | 270289.6 |